小叶买麻藤茎的化学成分研究

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1、万方数据硕士学位论文ThemajorchemicalconstituentfromC．aculeatus．arephenolicconstituentsandterpenoids，andonlypristimerinCanbedetectedbyTLC．Bypharmacognosticalidentification，microscopicidentification，Physicalandchemicalidentification，G．parvifoliumcouldbedistinguishedfromC

2、aculeatusaccuratelyandreliably．2．ThestudyonchemicalconstituentsfromlianasofG．parvifolium．4．5kgair-driedlianasG．parvifoliumwererefluxedwith95％ethanolat650Cfor3times(3hpertime)andfiltered．ThecombinedfiltrateWasconcentratedtoyieldcrudeextracts．Thecrudeextractswe

3、resuspendedinH20，andthenpartitionedwithpetroleumether(PE)，ethylacetate(EtOAc)andn-butylalcohol(n-BuOH)，consecutively．TheEtOAc-solutionfractionWassubjectedtocolumnchromatography(CC)forfurtherpurfication．Finally，20compoundswereisolatedthroughsilicagelCC，MCICC，O

4、DSCCandLH一20CC．BycomparingNMR，MSandotherspectraldataofthese20compoundswithrelevantliteratures，theirstructureswereidentifiedastwoaromaticacids：vanillicacid(1)and4-hydroxybenzoicacid(2)，fiveflavonoids：oroxylinA(3)，homoeriodictyol(4)，chrysoeriol(5)，5,7，2’一trihyd

5、roxyflavones(6)andnaringetol(7)，13stibenoids(including1trimericstilbene，6dimericstilbenes，5mono·stilbenes)：gnetifolinA(8)，pinosylvin(9)，isorhapontigenin(10)，resveratrol(11)，gnetol(12)，dihydropinosylvindiol(13)，ampelopsinF(14)，gnetuhaininE(15)，gnetuhaininN(16)

6、，gnetifolinC(17)，(-)-￡·viniferin(18)，cis-shegansuB(19)andparvifololD(20)．Amongthesecompounds，gnetuhaininN，pinosylvin，dihydropinosylvindiol，oroxylinA，chrysoerioland5,7，2’一trihydroxyflavonesarereportedfromG．parvifoliumforthefirsttime．OroxylinAand5,7，2’-trihydro

7、xyflavonearenewfortheGnetumLinn．TheaboveresultsconfirmedstibenoidsarethemajorandcharacteristicconstituentsofGnetumparvifolium．3．TheextractionandpurficationprocessstudyontotalstibenoidsfromlianasofG．parvifolium．Nowadays，Stibenoidsdemonstrateahugedemandinfields

8、ofmedicineandiii万方数据ABSTRACThealthcareproducts．ForG．parvifolium，stibenoidshaveagreatprospectstodevelopment．Byreferringtosimilarexperimentaldesigns，extractionandpurificationprocessesofstib