tgfβ1基因多态性与脑卒中的相关性研究

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1、硕士学位论文英文摘要group(P>O．05)．LogisticregressionanalysissuggestedthatneitheranygenotypesnoanyallelescouldincreasetheriskofonsetofCI(P>O．05)．2．ThedifferenceofthedistributionofTGFB1—800G>AgenotypesandalleleswasnotsignificantbetweentheCHandthecontrolgroupp>O．05)．Logis

2、ticregressionanalysissuggestedthatneitheranygenotypes110anyallelescouldincreasetheriskofonsetofCH妒>O．05)．3．Thedifferenceofthefrequencyof一800G>Agenotypesandallele●betweenthehypertensionsubgroupandtheno-hypertensionsubgroupof、J-theCIgroupwerenotsignificant(尸>O．

3、05)．msimilarresultWasobservedintheCHandthecontrolgroup俨>O．05)．．●’，4．nlemeanserulTllevelofTCofG：AcarriersandAAcarriersw弱，higherthanGGcarriersincontrolgroupaswellasinCIandCHgroup(尸<0．05)。1hemeanserul／llevelofLDL—CoftheGAcarriersandAAcarrierswashigherthantheGGca

4、rriersandthisWasexclusivelyobservedinthecontrolgroup．5．Thedifferenceofthefrequencyof一800G>Agenotypesandallele／、betweentheAP(atheroscleroticplaque)andtheWAP(withoutatheroscleroticplaque)groupWasnotsignificant∽O．05)，similarresultswereobservedaftercomparisonbetw

5、eentheAPsubgroupandWAP一subgroupinCI，CHandcontrolgroup．Therewasalsonosignificant，diffioffrequencyofgenotytand]Ideswasot；ervedbetweenrterenceo：ttrequencyofgenotyoesandallelesobservedbetweentheCI十APgroupandtheControl+APgroupaswellasbetweentheV硕士学位论文英文摘要CH+APgrou

6、pandcontrol+APgroupp0．05)．Conclusion：1．ThereisprobablynoassociationbetweentheTGFB1-800G>ApolymorphismandstrokeinhanpopulationinHunanprovince．2．TGFB1-800G>Apolymorphismisnotassociatedwithhypertensioninthepatientswithstrokeinadditiontothehealthypopulationinbanp

7、opulationinHunanprovince．3．ThereisprobablysomeassociationbetweentheTGFB1—800G>ApolymorphismandthemetabolismofTCandLDL—CinChinesehanpopulation．AallelemightbeanimportantfactorofaffectingtheserumlevelsofTCandLDL．C．4．ThereisprobablynoassociationbetweentheTGFB1—80

8、0G>Apolymorphismandatherosclerosisandthestabilityoftheatherosclerosticplaque．KEYWORDS：stroke，transforminggrowthfactor81，singlenucleotidepolymorphismVI硕士学位论文‘缩略词英文缩写缩略词简表英文全称TGFB1transform