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时间:2019-02-08
《低钙血症对脑出血预后的影响》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、万方数据史堡耋笙堕堂盘查!!!!生!旦笙!!鲞笙!塑篁!i!』鱼!生!!!:坠!∑!!!!:∑!!:!!!盟!:!低钙血症对脑出血预后的影响471·临床研究·沈和平王耿焕张晓玲官俏兵翟丽萍罗本燕310003浙江大学附属第一医院神经内科[沈和平(现在嘉兴学院附属第二医院神经内科工作)、罗本燕];314000嘉兴学院附属第二医院神经外科(王耿焕),神经内科(张晓玲、官俏兵、翟丽萍)通信作者:罗本燕,Email:luobenyan@zju.edu.cnD()l:10.3760/cma.j.issn.0254—9026.2016.005.004【摘要】目的前瞻
2、性研究探讨低钙血症对脑出血预后的影响。方法4lO例连续纳入的脑出血患者按发病12h内检测的血钙浓度分成低钙组、正常组、高钙组,同时详细记录分析每位患者的年龄、性别、人院时格拉斯哥昏迷评分(GCS)、血肿量等基线资料,6个月后随访,按格拉斯预后评分(G()s)评估预后,GOS大于3分为预后良好,GOS小于等于3分,为预后不良。结果低钙组有更低的GCS评分,更大的血肿量,手术比例高,再出血发生率高,6个月后预后不良率明显高于其他组。多因素Logistic回归分析校正其他可能影响因素,显示低钙血症组的预后比正常血钙组差(P<0.05),Oddsratio(O
3、R)值为3.01,95%CJ值为1.06~6.12。结论低钙血症是影响脑出血预后的独立危险因素。【关键词】低钙血症;脑出血;预后基金项目:嘉兴市科技局计划项目(NO.2014AY21038)ImpactanalysisofhypocalcemiaontheprognosisonintracerebralhemorrhageShenHeping,WangGenghuan,ZhangXiaoling,GuarlQiaobing,ZhaiLiping,LuoBenyanDepartmentofNeurology,TheFirstAJfiliatedHospi
4、taloJZhejiangUniversity,Hangzhou,310003,China(ShenHP,LuoBY);DepartmentofNP“rDs“rgPr_).,丁碥eSecondAffiliatedHospitalo-,’JiaxingUniversity,Jiaxing31400,China(WangGH);DepartmentoJNeurology,TheSecondAJJ‘iliatedHospitalofJiaxingUniversity,Jiaxing31400,China(ZhangXL,GuanQB,ZhaiLP)Ct’rr
5、esp‘mdingauthor:LuoBenyan,Email:luobenyan@zju.edu.cn[Abstract]ObjectiveToprospectivelyexploretheimpactofhypocalcemiaontheprognosticvalueofintracerebralhemorrhage.MethodsAtotalof410patientsconsecutivelyadmittedwithin12hoursafterintracerebralhemorrhageonsetweredividedinto3groupsba
6、sedonadmissionserumcalcium:lowserumcalciumgroup,normalserumcalciumgroupandhighserumcalciumgroup.Baselinecharacteristicsofpatientsincludingage,gender,Glasgowcomascore(GCS),hematomaVO】ume,etcwerecollectedandanalyzed.Afollow—upwasperformedafter6months,FinaloutcomewasassessedusingGl
7、asgowoutcomescale(G()S)withascore>3regardedasfavourableprognosis,ascore≤3asunfavourableprognosis.ResultsPatientswithlOWserumcalciumhadlowerGOS,biggerhematomavolume,higherrateofoperation,higherre-bleedingrate,moreunfavourableprognosisthandidtheother2serumcalciumgroups.Muhivariabl
8、eLogisticregressionanalysisshowedthatpatientswi
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