布洛芬化学拆分过程基础分析

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1、北京化工大学硕七学位论文detemlined．TheeXperiInentaldatawereregressedusedApelblaternpiricalequatioIl，andgotgoodfittingresult．Thec巧stall娩ationmetastablezoneofS—ibupro岛n刀-oc够l一小gluCaIninesaninetbanolwasdetemlined．Thesedatapr0Videthetlleorybasisforthec巧stalliza廿ontecllllologyofresolutionofibupro诧nand

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6、thebasisofresearchofcrystallizationthreomdyIllics，Ⅱle万一oc够l一小glucamiIlew嬲adopted嬲theresolutionagentt0s印aratetheibuprofenenantiomer，andresolutiontechllologyofibupro佗nwasstudiedandoptiInized矗．omthe邪pectsofmoleratioofibupro佗nto刀一oc够l-小glucamiIle，moleratioofethanolto刀一octyl一小glucamiIle，co

7、oliIlgtemperatI鹏，andmetimeofcryStalfom撕on．TheyicldofS—ibuprofenis36．02％andislligherman32％wllichwasr印onedbyre危renCe．KEYWoRDS：ibuprofe玛S—ibupr0￡n甩一oc够l一小glucanlinesan，cDrstanizationthem0Cbl，IlaIIlics，ttlemlodyna血c旬nction，。resolutiontecllllolOgyV目录目录第一章文献综述⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．11．1

8、手性药物概