时间空间相关成像技术对胎儿左室功能的分析

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1、Fetalleftcardiacfunctionassessedwithfour-dimensionalultrasoundimagingusingspatiotemporalimagecorrelationAbstractObjeetive：Theobjectiveofthisstudywastoquantifyfetusleftventricularvolumebetween22．39weeksinnormalandpathologicstateswiththespatiotemporalimagecorrelation(STIC)andvirtualorgancompu

2、ter-aidedanalysis(VOCAL)．Toestablishtherelationbetweenthenormalfetalleftventricularvolumeandgestation．estimatetheleftheart，Sfunctionbycalculatefetalcardiovascularparameters．InadditionweanalysisfetalventricularvolumeinpathologicstatestodiscussthefeasibilityandaccuracyofSTICestimatethedeforme

3、dfetalheanvolume．Studydesign：Thisstudysuccessfulgathered251women’Sven—tricularvolumedatasets(22-39weeksofgestation)usingtheSTICultrasoundtechnique．244fetusesarenormaland7fetusesareabnorrr'●●·一。mal．1heinclusioncriteriafornormalteamwereuncomplicatedsin。gletonpregnancywithnormalfetalanatomyand

4、growthdemonstrat。edbyultrasoundexamination，andgestafionalagedefinedbyakn-owndateoflastmenstrualperiodandconfirmedbyfetalbiometricmeasurements(HC，AC，FL)．Theabnormalfetuseswerediagnosedduri—ngthestudyperiodwithacardiacanomalywereexamined，andth-oseresultsweredemonstratedbydissectionorpostnatal

5、examinationThevolumedatasetsweregatheredduringfetalquiescencewithabdomenuppermost．CardiacventricularvolumeswerecalculatedinVOCALII．W．eidentifyend-systoleandend．diastolebyscrollingthr-ougheachframeandidentifyingtheimageprecedingtheAVvalveopening(systole)andfollowingAVvalveclosure(diastole)．T

6、heinnercontourofleftventricularin12planesweredrawnmanually,Thenavolumewascomputed．Thevolumedatasetswereusedtocalculates仃okevolume(SV)，cardiacoutput(CO)，andejectionfraction(EF)．ThisstudyadjustedCObytheestimatedfetalweight(EFW)，HC，AC，FLandanalysistherelationbetweenallparametersandgestation．IV

7、Result：Theresultmadefromthenormalteamwere：1、l1eftv．entricularvolume(bothsystoleanddiastole)，SV,COincreasedwitha-dvancinggestationalage0