复荣通脉胶囊对糖尿病大鼠肾脏pdgf-bb和mmp-9表达影响的实验分析

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1、英文摘要observation，foragestandards，theenvironmenttemperatureis22℃一26℃，theexperimentisnotusedduringtheinsulinandbloodsugar(or)otheroralglucose—loweringdrugsintervention．Lavagetreatmentfor8weeks，caudalveinbloodglucosemeasurement．with3％pentobarbitalsodium80mg／kgintraper

2、itonealinjectionofanestheticrats，midlineincisionabdomen，abdominalaorticblood，bloodsamples．Takebloodafterharvestingtheratkidney，removingrenalcapsuleandtherenalhilumconnectivetissueandphysiologicalsalineflushingafterweighing，willberecordedinthekidneyis1essthan0．5cmx

3、O．5cmx0．1cmtissueblock，at4％ofsexinformaldehydesolutionfixed，HEstainingunderlightmicroscopyobservationofglomerularandrenaltubularinterstitialpathologicalchanges，immunohistochemicalSPmethodtoobservethepathologicaltissuepositivestainingintheareaandintensity．Allthedat

4、awithSPSS16．0statisticalsoftwareprocessing，inspectionlevel：a=O．05．MeasurementdatawithX+SDsaid．Variancetogether，comparesthesinglefactoranalysisofvariancebetweengroups，groupcomparisonbeforeandafterthetreatmentusingmatchingttest．Results：1Buildinggroupsbeforetherats’b

5、loodsugarhasnostatisticalsignificance(尸>0．05)，comparedwithbeforetreatment，comparedwithNCgroup，DMgroupandFRL，FRM，FRHgroupratsbloodglucoseweresignificantlyhigher俨<0．05)，whiletheDMgroupandFRL，FRM，FRHbloodsugarisnostatisticalsignificancebetweengroups(p0．05)．Afterlavag

6、etreatmentfor8weeks，comparedwithNCgroup，DMgroupandFRL，FRM，FRHgroupbloodsugarofrats，weresignificantlyincreased(P<0．05)，whiletheDMgroupandFRL，FRM，FRHgroupratsbloodglucoseisnostatisticalsignificance俨>O．05)；Groupsofratsbloodglucosecomparedwithbeforetreatmenthasnoobvio

7、usdifference(P>0．05)．2Lavagetreatmentafter8weeks，comparedwithNCgroup，DMgroupandFRL，FRM，FRHTG，TClevelincreasedsignificantly(尸O．05)．3Lavagetreatmentafter8weeks，comparedwithNCgro

8、up，DMgroupandFRL，FRM，FRHScrandBUNlevelincreasedsignificantly(P0．05)，FRM，FRHgr