特发性甲旁减44例临床特点与相关因素分析

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1、特发性甲旁减44例l临床特点及相关因素分析2007级硕士研究生学位论文productbeforeandaftertreatmentwasnotsignificantlydifferent(P=O．125)；24·hoururinecalciumof30casesbelowthenormal，24casesbelowthenormal24一hoururinephosphorus．2．3FactorAnalysis：Epilepsyfatasapredictorofbraincalcification(P=0．041)；Cerebralcalcificationwasariskfactorof

2、epilepsy(b=1．168，OR=3．216，P=O．006)；Seizures(b_2．719，OR=15．162，P=0．014),duration(b=一0．024，OR卸．977，P=O．025)asriskfactorsforabnormalEECt2．4Correlationandregressionanalysis：Calciumandphosphoruswasanegativecorrelation(r=-0．388，P=0．009)，PhosphorusandbloodcalciumandphosphorusproductWasapositivecorrelatio

3、n(F0．801，P=-0．000)，thestandardizedregressioncoefficientofcalciumwas0．628(P=-0．ooo)，phosphorusstandardizedregressioncoefficientWas1．045(P=0．000)，namely,thecontributionrateofphosphorusoncalcium—phosphorusproductincreasesislargerthanthecalcium；Braincalcificationandmentalretardationwasapositivecorrela

4、tion(r--0．408，P=-0．01)，Cerebralcalcificationandepilepsywasapositivecorrelation(r=0．457，P--0．003)，AgeofonsetandbloodcalciumandphosphorusproductWasnegativecorrelation仁一0．494，P=0．001)，EEGabnormalitiesandseizuresWasapositivecorrelation(r=0．329,P=0．05)．3TreatmentprogramswereusingcalciumandvitaminDorder

5、ivativesthereof,treatment，promotionofexclusivephosphOruSandlowphosphorusdiet．Conclusion1thehighrateofmisdiagnosisanddelaylongcourse，thehighincidenceofbraincalcificationinIHP,andmorecommoninyoungchildren．2Hypocalcemia，hyperphosphatemia，andlowurinarycalciumandphosphorusaretheclinicalfeaturesofIHP；Se

6、rumcalciumandphosphorusinIHPpatientsexistanegativecorrelation，Serumcalcium，phosphorusandbloodcalcium—phosphorusproductexistsastraight—linerelationship，Andthecontributionrateofphosphorustotheriseofbloodcalcium—phosphorusproductwaslargethancalcium．Cerebralcalcificationandmentalretardationasapositive

7、correlation；cerebralcalcificationandepilepsyandmentalretardationexistpositiverelationship，Ageofonsetand4特发性甲旁减44例临床特点及相关因素分析2007级硕士研究生学位论文calcium-phosphorusproductexistanegativecorrelation，cerebralcalcificationwa