阿维菌素在中国登记现状与工业生产分析

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1、万方数据includingusecrops，controlobjects，dosageandresistancelevelsandSOon．Guangxi，Shandongservicelifehasreachedmorethan17years，andXinjiangbegantouseinthelast10years，followingthelongerlifeofavermectinformulation，theaverageresistancelevelhasbecomehigherandh

2、igher，whiletheaverageresistancelevelondifferentfruitcropsandvegetableswassignificantlygreatermanfieldcrops，whichisreleventedwiththeuseofavermectinonotherfruittreesandvegetablethanthefieldcrops．4．Itcurrentlyhas2559registrationcertificateofpesticidecomp

3、aniesinChina,amongwhich495aretheregisteredavermectinmanufacturers．Wedetaillyinvestigate29productioncompanies，removingthetwocompaniesofnospecificinvestigation，findingthatthereareseverloriginaldrugcompaniesinnormalproduction，andtheproductionofShandongQi

4、PharmaceuticalCo．，Ltd．，HebeiWeiyuanshenghuaPesticideCo．，Ltd．Shij}iazhuangCity-BaiBiologicalEngineeringCo．，Ltd．accountedfor72．5percentoftotalnationalproduction．Avermectinoriginaldrugindustrialproductionprocessesinclude：transformationofbacteriainoculate

5、dfermentation，refiningpure．Avermectinproduction,cost，qualityandspeciesleveliscritical，thecurrentdomesticproductionenterprisesbacteriafermentationunitCanreach6500pg／mlormore．Theinvestigationshowedthatinthepurificationofavermectinproductionprocess，theyi

6、eldisgenerally70％-80％，whiletheyieldofoutstandingmanufacturersCanreachmorethan85％．AtpresenttheAvermectinoriginaldrugmanufacturersforexhaustgastreatmentismainlyplasmaandadsorptionfiltration，wastewatertreatmentismainlyanaerobicandaerobicbiologicalcontact

7、oxidationprocess，mainlytheburningofwastetreatmentiscurrentlybased．Keyword：Avermectin；biologicalpesticides；pesticideregistration；marketanalysis；industrialoptimization万方数据目录1引言⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯一l1．1研究背景⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯

8、⋯⋯⋯⋯一11．2研究目的意义⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯一5113本论文研究思路⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯一52研究方法⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯62．1阿维菌素的登记现状分析⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯62．2阿维菌素制剂在全国的使用情况调查⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯一62．3阿维菌素在全国的抗药性情况调查⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯一62．4阿维菌素原药