资源描述：
《mb和ck-mb／ck比值在诊断多发伤合并心肌损伤中的临床意义》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、MB和CK-MB/CK比值在诊断多发伤合并心肌损伤中的临床意义创伤外科杂志2006年第8卷第4期JTniunKiSurg,2006,Vol.&No.4文章编号：1009-4237(2006)04—0307-039■307?9■论着？CK,CK—MB和CK—MB/CK比值在诊断多发伤合并心肌口71LJ*刘小玲.(1•重庆市急救医疗中心检验科，重庆损伤中的临床意义，孔令文，都定元,程颖.400014;2.重庆市急救医疗中心胸心外科，重庆400014)摘要:目的探讨肌酸激酶(CK),肌酸激酶同功酶(CK.MB)和CK.MB/CK比值在诊断多发伤合并心肌损伤中的临床意义•方
2、法选择多发伤患者104例,分为合并心肌损伤组41例(A组)，无合并心肌损伤组63例(B组)，分别进行损伤严重度评分(ISS),并采集血样测定CK,CK.MB,计算CK-MB/CK比值，同时记录12导联心电图.结果ISS值与CK峰值呈正相关・A组CK—MB峰值及CK-MB/CK比值升高率明显高于B组(P<0.05).CK.MB和CK.MB/CK比值在诊断心肌损伤中的敏感性，特界性,准确性，阳性似然比和阴性似然比分别为:CK-MB92.12%,69.13%,80.4J4%,2.98,0.114;CK-MB/CK90.70%,87.23%,86.52%,7.10,0
3、.106.结论多发伤患者损伤赵严重血清CK峰值也越高;CK-MB和CK-MB/CK比值是诊断多发伤心肌损伤的较好指标，且CK.MB/CK比值诊断价值优于CK-MB.关键词:多发伤;损伤严重度评分;心肌损伤;肌酸激酶;肌酸激酶/肌酸激酶同功酶中图分类号:R654.2文献标识码:AClinicalsignificanceofCK.CK-MBandCK-MB/CKratioindiagnosisofmultipletraumaswithmyocardialdamageLlUXiao一ling,KONGLing-wen,DU,lg-yll~lZ,etal・(Departme
4、ntofLaboratoryInvestigation,ChongqingEinergencyMedicalCenter,Chongqing400014,China)Abstract:ObjectiveToexploretheclinicalsignificanceofCK,CK-MBandCK-MB/CKratiointhediag-nosisofmultipletraumaswithmyocardialdamage.MethodsTheclinicaldataofl04casesofmuItipIetraumasWasanalyzedretrospectivel
5、y.Thecasesweredividedinto2groups,themultipletraumaswithmyocardialdamagein41cases(Agroup),andmultipletraumaswithoutmyocardialdamagein63cases(Bgroup).Theinjuryseverityscore(ISS)wascalculatedusingAIS98.TheCK,CK-MBandCK-MB/CKratioofbloodsampleswere&easuredandECGWasrecordedinallthecases
6、.ResultsISSandCKpeakvalueswerepositivelycorrelated.TheCK-MBpeakvalueandCK-MB/CKratioofAgroupweresignificantlyhigherthanthatofgroupB(P<0.05).Thesensitiv-ity,specificity,degreeofaccuracy,positivelikelihoodratioandnegativelikelihoodratioofCK-MBandCK-MB/CKratiowere92.12%t69.13t80.44%t2.
7、98,0.114,90.70%,87.23,86.52,7.10,0.106respectively-ConclusionISSandCKpeakvalueswerepositivelycorrelatedinthepatientsofgroupA.TheCK-MBandCK・MB/CKratiowerebetterindexesinthediagnosisofmultipletraumawithmyocardialdamageKeywords:multipleinjuries;ISS;myocardialdamage;CK-MB;CK-MB/CK多发伤是目前创
