克林霉素联合庆大霉素治疗慢性盆腔炎的临床观察

《克林霉素联合庆大霉素治疗慢性盆腔炎的临床观察》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。

1、克林霉素联合庆大霉素治疗慢性盆腔炎的临床观察蔺红霞(西安市西仪集团医院妇产科陕西西安710082)【摘要】目的：探讨克林霉素联合庆大霉素治疗慢性盆腔炎的临床疗效和安全性。方法：将86例慢性盆腔炎患者分为两组，对照组采用庆大霉素联合甲硝哇治疗，观察组采用克林霉素联合庆大霉素治疗，均连续治疗2周观察两组临床疗效和不良反应，并观察两组治疗前后临床症状积分变化。结果：观察组总有效率93.02%显著高于对照组的79.07%,不良反应发生率11.63%显著低于对照组，差异有统计学意义(P<0.05)；两组治疗后临床症状积分均较治疗前显著降低，且观察组治疗后低于对照组治疗后，差异有

2、统计学意义(P<0.05)o结论：克林霉素联合庆大霉素治疗慢性盆腔炎临床疗效显著，可以有效改善患者的临床症状,且不良反应少，值得临床积极推广。【关键词】克林霉素；庆大霉素；慢性盆腔炎；疗效；安全性【中图分类号】R711.33【文献标识码】A【文章编号】2095-1752(2016)23-0134-02ClinicalobservationofclindamycinandgentamicininthetreatmentofchronicpelvicinflammationLinHongxia・Departmentofgynaecologyandobstetrics,X「

3、anXiyigroupHospital,Shaanxi,Xi'an710082,China[Abstract]ObjectiveToexploretheefficacyandsafetyofclindamycinandgentamicininthetreatmentofchronicpelvicinflammatorydisease.Methods86casesofchronicpelvicinflammationpatientsweredividedintotwogroups,thecontrolgroupusinggentamicinandmetronidazol

4、efortreatment,theobservationgroupwerecombinedwithclindamycinandgentamicintreatment,continuoustreatmentfor2weekstoobservetheclinicalefficacyandadversereactionsoftwogroups,andobservethechangesofintegraltheclinicalsymptomsofthetwogroupsbeforeandaftertreatment.ResultsThetotaleffectiverateof

5、observationgroup(93.02%)wassignificantlyhigherthanthecontrolgroup79.07%,theincideneeofadversereactions(11.63%)wassign讦icantlylowerthanthecontrolgroup,thediffereneewasstatisticallysignificant(P<0.05);thetwogroupsclinicalsymptomscoresaftertreatmentweresignificantlylowerthanthosebeforet

6、reatment,andthepatientsintheobservationgroupthaninthecontrolgroupaftertreatment.Thedifferencewasstatisticallysign讦icant(P<0.05).ConclusionClindamycinandgentamicinhavesignificanttherapeuticeffectinthetreatmentofchronicpelvicinflammatorydisease,caneffectivelyimprovetheclinicalsymptomso

7、fpatientsShape,andlessadversereactions,itisworthclinicalpromotionpositively.【Keywords]Clindamycin;Gentamicin;Chronicpelvicinflammation;Efficacy;Safety慢性盆腔炎是常见的妇科疾病，是女性内生殖器和周围结缔组织、盆腔腹膜发生的慢性炎症。近年来随着抗生素的不合理使用，引起细菌耐药性的增加，慢性盆腔炎的治疗效果不佳，病情反复，而长期炎症会对女性内生殖器产生刺激，从而引起盆腔器官周围组织增厚和粘连，严重影响患者的