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1、AnIntroductiontoMedicinalChemistryGRAHAML.PATRICKDepartmentofChemistry,PaisleyUniversityOxfordNewYorkTokyoOXFORDUNIVERSITYPRESS1995OxfordUniversityPress,WaltonStreet,OxfordOX26DPOxfordNewYorkAthensAucklandBangkokBombayCalcuttaCapeTownDaresSalaamDelhiFlorenceHongKongIstanbulKarachiKualaLumpu
2、rMadrasMadridMelbourneMexicoCityNairobiParisSingaporeTaipeiTokyoTorontoandassociatedcompaniesinBerlinIbadanOxfordisatrademarkofOxfordUniversityPressPublishedintheUnitedStatesbyOxfordUniversityPressInc.,NewYork©GrahamL.Patrick,1995Allrightsreserved.Nopanofthispublicationmaybereproduced,store
3、dinaretrievalsystem,ortransmitted,inanyformorbyanymeans,withoutthepriorpermissioninunitingofOxfordUniversityPress.WithintheUK,exceptionsareallowedinrespectofanyfairdealingforthepurposeofresearchorprivatestudy,orcriticismorreview,aspermittedundertheCopyright,DesignsandPatentsAct,1988,orinthe
4、caseofreprographicreproductioninaccordancewiththetermsoflicencesissuedbytheCopyrightLicensingAgency.EnquiriesconcerningreproductionoutsidethesetermsandinothercountriesshouldbesenttotheRightsDepartment,OxfordUniversityPress,attheaddressabove.Thisbookissoldsubjecttotheconditionthatitshallnot,
5、bywayoftradeorotherwise,belent,re-sold,hiredout,orotherwisecirculatedwithoutthepublisher'spriorconsentinanyformofbindingorcoverotherthanthatinwhichitispublishedandwithoutasimilarconditionincludingthisconditionbeingimposedonthesubsequentpurchaser.Acataloguerecordforthisbookisavailablefromthe
6、BritishLibraryLibraryofCongressCataloginginPublicationDataPatrick,GrahamL.AnintroductiontomedicinalchemistryIGrahamL.Patrick.—1sted.Includesbibliographicalreferencesandindex.1.Pharmaceuticalchemistry.I.Title.RS403.P381995615/.19—dc2094-24704ISBN0198558724(Hbk)ISBN0198558716(Pbk)TypesetbyFoo
7、tnoteGraphics,Warminster,WiltsPrintedinGreatBritainonacid-freepaperbytheBathPressPrefaceThistextisaimedatundergraduateswhohaveabasicgroundinginchemistryandareinterestedinafuturecareerinthepharmaceuticalindustry.Itattemptstoconveysomethingofthefascination
