资源描述：
《多形性胶质母细胞瘤的临床综合治疗进展》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、英文摘要TheprogressofclinicalcomprehensivetreatmentforglioblastomamultiformeABSTRACTObjective:concludetheprogressofclinicalcomprehensivetreatmentforglioblastomamultiforme.Content:theglioblastomamultiformeisthemostcommonprimarymalignanttumorinbrain,whichmalignantdegreeisextr
2、emelyhigh.Evenifusingstandardizedtreatment,patientsstillfacetumorrecurrenceandevendeath.Herereviewedthedomesticandforeignperiodicalsandtreatmentguidelinesinrecentyears,summarizedtheclinicalcharacteristicsandlistedthetreatmentprocessofthestatusquoandnewdirectionincluding
3、surgery,radiationtherapy,chemotherapy,targetedtherapyandimmunotherapy,evenanalyzedtheefficacyandsafetyofimmunotherapyincludingvaccines,adoptiveTcelltherapy,immunecheckpointblockade,monoclonalantibody,cytokinetherapyandimmunomodulatorytherapy.Methodsandresults:usingofnet
4、workresourcestofindthedomesticandforeignjournalsandtreatmentguidelinesinrecentyears,withacarefulreadingandtranslation.Conclusion:whentheglioblastomamultiformtreatedwithstandardizedtreatmentatthesametime,stillshouldcontinuetopromotetheoperationmethods,increasethemeansand
5、waysoftreatment.Keywords：Glioblastomamultiforme,Surgery,Radiationtherapy,Chemotherapy,Standardizedtreatment,Targetedtherapy,Immunetherapy2万方数据英文缩写英文缩写英文缩写英文全称中文全称GBMGlioblastomamultiforme多形性胶质母细胞瘤WHOWorldhealthorganization世界卫生组织MRIMagneticResonanceImaging磁共振成像GFAPGlialf
6、ibrillaryacidicportein胶质纤维酸性蛋白PFSProgressionfreesurvival无进展生存期OSOverallsurvival总生存期IDHIsocitratedehydrogenase异柠檬酸脱氢酶KPSKarnofskyPerformanceStatus卡罗斯基FLFluorescein荧光素钠MRSMagneticResonancespectroscopy磁共振波谱分析RTOGRadiationTherapyOncology美国肿瘤放射治疗协作Group组EORTCEuropeanOrganiza
7、tionfor欧洲癌症治疗研究组织ResearchandTreatmentofCancerMGMTO6-methylguanine-DNA六氧甲基鸟嘌呤DNA甲methyltransferase基转移酶NAA1-Naphthylaceticacid1-萘基乙酸ChoCholine胆碱IVIMIntravoxelIncoherentMotion体素内不相干运动ImagingDWIDiffusionWeightedImaging磁共振弥散加权成像
ADCApparentdiffusioncoefficients表观扩散系数
CBVCere
8、bralbloodvolume脑血容量ASLArterialspinlabeling动脉自旋标记
PWIPerfusionweightedimaging磁共振灌注加权成像
PETPositronemissiontomog
