资源描述：
《前列腺癌Gleason评分与PSA、MRI的相关性研究.doc》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。
1、前列腺癌根治术后病理分期、Gleason评分与术前血清PSA的相关性研究吕志勇1，3，吴志辉2，吴小侯3(750004银川,宁夏医科大学附属医院泌尿外科1；999077香港,中国香港中文大学附属威尔斯亲王医院泌尿外科2；400016重庆,重庆医科大学附属医院泌尿外科3)[摘要]目的探讨前列腺癌患者根治术后病理分期、Gleason评分与术前血清PSA的相关性。方法收集香港中文大学附属威尔斯亲王医院泌尿外科2008年1月至2010年9月采用4-臂daVinciS-HD机器人外科手术系统施行前列腺根治性切除术的100例前列腺癌患者的临床资料数据，采用Spearman等级
2、相关分析探讨根治术后病理分期、Gleason评分与术前血清PSA的相关性。结果本组患者PSA值与Gleason评分呈正相关（r=0.382,P＜0.01），PSA值越高，Gleason评分值越高。PSA值与病理分期无明确的相关性(r=-0.073,P>0.05)。结论前列腺癌患者术前血清PSA与根治术后Gleason评分有关，与病理分期无明确的相关性。[关键词]前列癌;前列腺特异性抗原;Gleason评分;病理分期[中图法分类号][文献标志码]ARelationshipofserumPSAandGleasonscore,pathologicalstageafter
3、radicalprostatectomyinpatientswithprostatecancerLVZhiyong1，3,CFNG2,WuXiaohou3(1DepartmentofUrology,TheAffiliatedHospitalofNingxiaMedicalUniversity,Yinchuan750004；2DivisionofUrology,DepartmentofSurgery,TheChineseUniversityofHongKong,PrinceofWalesHospital,HongKong999077；3DepartmentofUro
4、logy，theFirstAffiliatedHospital，ChongqingMedicalUniversity，Chongqing，400016，China)[Abstract]ObjectiveToevaluatetherelationshipsbetweenserumPSA(prostatespecificantigen)andGleasonscore,pathologicalstageafterradicalprostatectomyinpatientswithprostatecancer.MethodsAsurveyhasbeenmadeon100i
5、npatientswithprostatecancerunderwentrobot-assistedlaparoscopicradicalprostatectomy(rLRP)byadedicatedteamusingthedaVinciroboticsurgicalsystemfromJan2008toSep2010intheDivisionofUrology,DepartmentofSurgery,TheChineseUniversityofHongKong,PrinceofWalesHospital.Spearmanrankcorrelationwasapp
6、liedtoevaluatetherelationshipbetweenGleasonscore,pathologicalstageafterradicalprostatectomyandtotalPSA.ResultsIn100casesofprostatecancer,totalPSAwassignificantlypositivelycorrelatedwithGleasonscore(r=0.382,P＜0.01),butnotsignificantlycorrelatedwithpathologicalstage(r=-0.073,P>0.05).Con
7、clusionSerumtotalPSAarecorrelatedwithGleasonscorebutnotcorrelatedwithpathologicalstage.[Keywords]prostaticcancer;prostatespecificantigen;Gleasonscore;pathologicalstageCorrespondingauthor:LVZhiyong,Tel:86-951-6743248，E-mail:lvlu1996@sina.com［通信作者］吕志勇，电话：（0951）6743248，E-mail:lvlu1996@si
8、na.co
