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1、产儿出生缺陷的发生状况及相关危险因素分析(江苏省常州市金坛区妇幼保健所江苏常州213200)【摘要】目的:探讨分析我区出生缺陷的发生状况及相关危险因素。方法:将2011年1月至2015年12月期间在我区分娩成功的22916例新生儿作为研究分析对象,回顾分析其临床资料,记录出生缺陷状况,并对出生缺陷因素进行分析。结果:2011年至2015年期间,共分娩22916例,出生缺陷共88例,占比为3.8‰。88例出生缺陷中,包含16例多指、19例唇裂、21例祌经和智力缺陷、17例先天心脏病、15例肢体缺陷。经调查后得知
2、,出生缺陷的研究组和新牛JL正常的对照组,从产妇流产史、孕期感染、服用药物、吸烟等状况,以及家庭缺陷史方面来看,研究组发生率均比对照组要高,组间差异有统计学意义(P<0.05)o结论:围产儿出生缺陷发生率虽存在逐步上升状况,但仍然处于我省和国家相关规定范围内,造成此类状况的因素主要由家庭缺陷史、孕产妇生活习惯、药物使用、流产状况等存在关系,因此,孕期定期进行产检,加强孕前、孕期健康知识宣教尤为重要。【关键词】孕产妇;出生缺陷;相关因素【中图分类号】R174【文献标识码】A【文章编号】2095-1752(2016)27
3、-0028-02AnalysisontheoccurrencestatusandrelatedriskfactorsofperinatalbirthdefectsXuYunmei.MaternalandChildhealthCareCenterofJintanDistrict,ChangzhouCity,JiangsuProvince,Changzhou213200,China[Abstract]ObjectiveTostudytheanalysisoftheoccurrenceofbirthdefectsindevelo
4、pmentofourstatusandrelatedriskfactors.MethodsFromJanuary2011toDecember2015inourdistrictduringdeliverysuccessful,22916casesofneonatalasstudyobject,Retrospectiveanalysistheclinicaldata,recordthebirthdefects,andanalyzethefactorsofbirthdefects.ResultsDuring2011to2015,
5、22916caseswithbirth,birthdefects,atotalof88cases,accountedfor3.8‰.Of88casesofbirthdefects,Containmorethan16cases,19casesofcleftlip,21casesofneurologicalandmentalretardation,17casesofcongenitalheartdisease,15casesoflimbdefects.Afterinvestigation,thebirthdefe
6、ctsoftheteamandnewbornsofnormalcontrolgroup,Fromthematernalhistoryofmiscarriage,pregnancyinfection,takingdrugs,smokingstatus,Incidenceofdefects,andfamilyhistoryperspective,theteamareallhigherthanthecontrolgroup,Thedifferencebetweengroupswasstatisticallysignificant
7、(P<.05).ConclusionAlthoughtheincidenceofperinatalbirthdefectsaregraduallyrising,butstillinourprovinceandtherelevantprovisionsofthestate,Factorscausingsuchasituationismainlycomposedoffamilyhistoryofdefects,maternalhabits,druguse,theconditionofabortion,relationsh
8、ip,Aregularprenatalpregnancy,therefore,tostrengthenpregnancy,pregnancyhealthknowledgeeducationisparticularlyimportant.【Keywords]Maternal;Birthdefects;Re