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1、无创呼吸机联合纳洛酮治疗老年COPD并呼吸衰竭的临床研宄庞先琼徐华赵学会(四川省西充县人民医院呼吸科四川西充637200)【摘要】A的研宄无创呼吸机联合纳洛酮治疗老年阻塞性肺病的临床效果。方法选取2010年3月〜2013年2月间入院诊治的老年COPD合并呼吸衰竭的患者120例，随机分为实验组(60例)和对照组(60例)，其屮对照组单纯应用无创呼吸机治疗，实验组在对照组基础上联合纳洛酮治疗。疗程结束后观察两组患者的治疗效果及呼吸、心率、动脉血气指标等。结果实验组显效25例，好转29例,总有效率为90.00%；对照组显效15例，好转30例，总有效率为75
2、.00%。两组患者PaO2、PaCO2、PH、SpO2等动脉血气指标与治疗前相比均有所改善，丑实验组疗效更优。上述数据均具有统计学意义(P<0.05)。结论无创呼吸机联合纳洛酮治疗老年阻塞性肺疾病具有良好的疗效，可显著改善动脉血气指标,提高患者的生活质量。【关键词】无创呼吸机联合纳洛酮老年COPD呼吸衰竭疗效【中图分类号】R45【文献标识码】A【文章编号】2095-1752(2014)16-0041-02Clinicaleffectsofnon-invasiveventilationcombinedwithnaloxonetoelderlyCO
3、PDpatientswithrespiratoryfailurePangxian-qiong，Xu-hua,Zhaoxue-hui(DepartmentofRespiratory,ThePeople'shospitalofXichong.Xichong,Sichuan,China637200)[Abstract]ObjectiveTostudytheclinicaleffectsofnon-invasiveventilationcombinedwithnaloxonetoelderlypatientswithobstructivepulmonaryd
4、isease.Methods120elderlyCOPDpatientswithrespiratoryfailurehospitalizedfromMarch2010–February2013wererandomlydividedintoexperimentalgroup(60cases)andcontrolgroup(60cases).Thecontrolgroupweretreatedwithnon-invasiverespiratorymachinetreatment,andtheexperimentalgroupwerebased
5、onthecombinationofbothnon-invasiverespiratorymachineandnaloxone.Respiration,heartrate,arterialbloodgaswereutilizedasindicatorsoftherapeuticeffectsofbothgroups.Results25caseswithsignificanteffectswereobservedinexperimentalgroup,aswellas29caseswithrelativeeffects,thetotaleffectiv
6、eratewas90.00%;15caseswithsignificanteffectswereobservedincontrolgroup,aswellas30caseswithrelativeeffects,thetotaleffectiveratewas75.00%.PaO2,PaCO2,PH,SpO2andotherindicatorsofarterialbloodgaseswereallimprovedinbothgroupsaftertreatment,withbetterefficacyinexperimentalgroup.Allda
7、tawerestatisticallysignificant(P<0.05).Conclusionnon-invasiveventilationcombinednaloxonehasgoodefficacyintheatingsenileobstructivepulmonarydiseaseandinamelioratingarterialbloodgasindicators„whichconsequentlycontributestobetterlifequality.【Keywords】noninvasiveventilatorjointn
8、aloxoneelderlyCOPDrespiratoryfailureefficacy慢性阻塞性肺疾病(C
