不同靶器官损害高血压患者红细胞分布宽度水平变化的研究

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1、観2018-03-2910:29:58中国现代医生2018年6期吴轶柯淑兰项伟忠潘铨陈礼平［摘耍］鬥的探讨不同靶器官损害高血压患者及健康体检者之间红细胞分布宽度(redbloodcelldistributionwidth,RDW)是否存在差异。方法选择2015年1月〜2016年12月于丽水市巾医院治疗的髙血压患者200例，以及同期年龄匹配的健康体检者50例作为健康对照组。根据合并靶器宵损杏的怙况，将商血压患者分为商血压合并颈动脉粥样硬化(atherosclerosis,AS)组、高血压合并早期肾损害组、卨血压合并左心室肥厚(

2、leftventricularhypertrophy,LAH)组、高血ffi合并2种祀器官组、高血压合并3种靶器官损害组、单纯高血压组共6个亚组。检测并记录各组RDW值，比较各组间RDW差异，分析RDW与商血压靶器官损害的关系。结果萵血压各亚组及健康对照组间RDW水T•差异显著(P<0.05)o髙血压合并靶器官损害组RDW值均髙于单纯髙血压组(P<0.05)，单纯商血压组RDW值商于健康对照组(P<0.05)，其余各组间RDW值两两比较，差异无统计学意义(P>0.05)。结论RDW与高血压以及高血压靶器官损害之间存在一定关系

3、，RDWwJ作为高血压疾病进展和严重程度的一项评价指标。［关键词］高血压；红细胞分布宽度：颈动脉粥样硬化；早期肾损害：左心室肥厚［中图分类号］R544.1［文献标识码］A［文章编号】1673-9701(2018)06-0004-05［Abstract］ObjectiveToinvestigatewhetherthereisadifferenceinredbloodcelldistributionwidth(RDW)betweenhypertensivepatientswithdifferenttargetorgandamag

4、eandhealthysubjects.Methods200hypertensivepatientsinLishuiHospitalofTraditionalChineseMedicinefromJanuary2015toDecember2016wereselectedand50healthysubjectsofthesameageinthesameperiodwerechosenashealthycontrolgroup.Thehypertensivepatientsweredividedintohypertensionc

5、ombinedwithatherosclerosis(AS)group,hypertensioncombinedwithearlyrenalimpairmentgroup,hypertensioncombinedwithleftventricularhypertrophy(LAH)group,hypertensioncombinedwithtwokindsoftargetorgansgroup，hypertensioncombinedwiththreetypesoftargetorgandamagegroupandhyper

6、tensiongroup.TheRDWvalueofeachgroupwasdetectedandrecorded.ThedifferencesofRDWamongthegroupswerecompared.TherelationshipbetweenRDWandtargetorgandamageofhypertensionwasanalyzed.ResultsThereweresignificantdifferencesinRDWlevelsbetweenhypertensionsubgroupsandhealthycon

7、trols(P<0.05)•ThevalueofRDWinhypertensioncombinedwithtargetorgandamagegroupwashigherthanthatinhypertensiongroup(P<0.05)•RDWinhypertensiongroupwashigherthanthatinhealthycontrolgroup(P<0.05)•TherewasnostatisticallysignificantdifferenceinRDWvaluesbetweentheothergroups

8、(P>0.05).ConclusionThereisarelationshipbetweenRDWandhypertensionandhypertensivetargetorgandamage.RDWcanbeusedasanevaluationindexfortheprogression