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时间:2018-12-06
《赣南地区糖化血红蛋白与2型糖尿病患者慢性并发症的相关性研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、赣南地区糖化血红蛋白与2型糖尿病患者慢性并发症的相关性研究摘要:目的调研赣南地区2型糖尿病患者(T2DM)糖化血红蛋口(HbAlc)的水平与其慢性并发症的关系。方法选取我院2014年1月〜2016年1月内分泌科就诊的500例2型糖尿病患者,根据HbAlc水平分为三个组:A组W7.0%、B组7%2、),与HbAlc呈正相关;随着HbAlc水平上升,糖尿病视网膜病变(DR)、糖尿病肾病和冠心病、脂肪肝的发病率升高(P〈0.05)。糖尿病周围神经病变、糖尿病足(DF)和脑梗死的发病率组间差异无统计学意义。结论糖尿病患者的慢性并发症的发生随着HbAlc的升高而增加,积极严格控制2型糖尿病患者的HbAlc冇利于防治糖尿病并发症的发生于发展。关键词:糖化血红蛋白;2型糖尿病;慢性并发症TheCorrelationStudyofGlycosylatedHemoglobinandChronicComplication3、sinType2DiabetesofGarmanAreaZHONGShu-mei,YINYing,ZHANGSi-qing,ZENGXian-zhong,XIYan-hua,LIXiao-yan(DepartmentofEndoerinologyandMetabolism,GanzhouPeople'sHospital,Ganzhou341000,Jiangxi,China)Abstract:ObjectiveTostudythecorrelationofglycosylatedhemoglobinandch4、roniccomplicationsintype2diabetesofGaimanarea・Methods500casesoftype2diabetespatientsinourdepartmentofEndocrinologyfromJanurary2014toJanurary2016.AccordingtotheHbAlctheyweredividedintoAgroup^7.0%,Bgroup7%5、easuredanddiabeticcomplicationswerescreenedinallsubjects.ResultsTherewasnosignificantdifferenceinbloodpressure,TCandHDL-Camongthreegroups(P<0.05)・TherewerestatisticallysignificantdifferencesinFBG,TGandLDL-C(P<0.05),andpositivelycorrelatedwiththeHbAlc.Theinc6、ideneeofdiabeticretinopathy(DR),coronaryheartdisease(CHD),diabeticnephropathy(DN)andfattyliverincreasedmarkedlyalongwiththeelevationofHbAlclevels(P<0.05)・Therewasnosignificantdiffercnccintheincidenceofdiabeticperipheralneuropathy(DNP),cerebralinfarctionandd7、iabeticfoot・ConelusionChroniccomplicationsindiabeticpatientscloselyrelatedtoglycosylatedhemoglobincontent,dwithelevatedHbAlcincrease,strictcontroloftype2diabetesHbAlcinfavorofpreventionandtreatmentofdiabeticcomplicationsoccurindevelopment・Keywords:Glycosyla8、tedhemoglobin;Type2diabetes;Chroniccomplications糖尿病慢性并?1症随着糖尿病发病率的增加而呈逐年增加的趋势[1],并成为糖尿病致残与早亡的最主要原因,严重威胁人类健康[2]。我国作为糖尿病发病大国[3],目前治疗糖尿病及并发症已成为公共卫生问题[4],给家庭和社会带了巨大的经济压力,因此加强糖尿病的诊断、监控和并发症的防治具有非常现实而重要的意义。糖化
2、),与HbAlc呈正相关;随着HbAlc水平上升,糖尿病视网膜病变(DR)、糖尿病肾病和冠心病、脂肪肝的发病率升高(P〈0.05)。糖尿病周围神经病变、糖尿病足(DF)和脑梗死的发病率组间差异无统计学意义。结论糖尿病患者的慢性并发症的发生随着HbAlc的升高而增加,积极严格控制2型糖尿病患者的HbAlc冇利于防治糖尿病并发症的发生于发展。关键词:糖化血红蛋白;2型糖尿病;慢性并发症TheCorrelationStudyofGlycosylatedHemoglobinandChronicComplication
3、sinType2DiabetesofGarmanAreaZHONGShu-mei,YINYing,ZHANGSi-qing,ZENGXian-zhong,XIYan-hua,LIXiao-yan(DepartmentofEndoerinologyandMetabolism,GanzhouPeople'sHospital,Ganzhou341000,Jiangxi,China)Abstract:ObjectiveTostudythecorrelationofglycosylatedhemoglobinandch
4、roniccomplicationsintype2diabetesofGaimanarea・Methods500casesoftype2diabetespatientsinourdepartmentofEndocrinologyfromJanurary2014toJanurary2016.AccordingtotheHbAlctheyweredividedintoAgroup^7.0%,Bgroup7%5、easuredanddiabeticcomplicationswerescreenedinallsubjects.ResultsTherewasnosignificantdifferenceinbloodpressure,TCandHDL-Camongthreegroups(P<0.05)・TherewerestatisticallysignificantdifferencesinFBG,TGandLDL-C(P<0.05),andpositivelycorrelatedwiththeHbAlc.Theinc6、ideneeofdiabeticretinopathy(DR),coronaryheartdisease(CHD),diabeticnephropathy(DN)andfattyliverincreasedmarkedlyalongwiththeelevationofHbAlclevels(P<0.05)・Therewasnosignificantdiffercnccintheincidenceofdiabeticperipheralneuropathy(DNP),cerebralinfarctionandd7、iabeticfoot・ConelusionChroniccomplicationsindiabeticpatientscloselyrelatedtoglycosylatedhemoglobincontent,dwithelevatedHbAlcincrease,strictcontroloftype2diabetesHbAlcinfavorofpreventionandtreatmentofdiabeticcomplicationsoccurindevelopment・Keywords:Glycosyla8、tedhemoglobin;Type2diabetes;Chroniccomplications糖尿病慢性并?1症随着糖尿病发病率的增加而呈逐年增加的趋势[1],并成为糖尿病致残与早亡的最主要原因,严重威胁人类健康[2]。我国作为糖尿病发病大国[3],目前治疗糖尿病及并发症已成为公共卫生问题[4],给家庭和社会带了巨大的经济压力,因此加强糖尿病的诊断、监控和并发症的防治具有非常现实而重要的意义。糖化
5、easuredanddiabeticcomplicationswerescreenedinallsubjects.ResultsTherewasnosignificantdifferenceinbloodpressure,TCandHDL-Camongthreegroups(P<0.05)・TherewerestatisticallysignificantdifferencesinFBG,TGandLDL-C(P<0.05),andpositivelycorrelatedwiththeHbAlc.Theinc
6、ideneeofdiabeticretinopathy(DR),coronaryheartdisease(CHD),diabeticnephropathy(DN)andfattyliverincreasedmarkedlyalongwiththeelevationofHbAlclevels(P<0.05)・Therewasnosignificantdiffercnccintheincidenceofdiabeticperipheralneuropathy(DNP),cerebralinfarctionandd
7、iabeticfoot・ConelusionChroniccomplicationsindiabeticpatientscloselyrelatedtoglycosylatedhemoglobincontent,dwithelevatedHbAlcincrease,strictcontroloftype2diabetesHbAlcinfavorofpreventionandtreatmentofdiabeticcomplicationsoccurindevelopment・Keywords:Glycosyla
8、tedhemoglobin;Type2diabetes;Chroniccomplications糖尿病慢性并?1症随着糖尿病发病率的增加而呈逐年增加的趋势[1],并成为糖尿病致残与早亡的最主要原因,严重威胁人类健康[2]。我国作为糖尿病发病大国[3],目前治疗糖尿病及并发症已成为公共卫生问题[4],给家庭和社会带了巨大的经济压力,因此加强糖尿病的诊断、监控和并发症的防治具有非常现实而重要的意义。糖化
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