米非司酮联合桂枝茯苓胶囊在治疗子宫肌瘤中的疗效观察

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1、米非司酮联合桂枝茯苓胶囊在治疗子宫肌瘤中的疗效观察河南省济源市人民医院妇科刘玖玖摘要：目的：观察米非司酮联合桂枝茯苓胶囊在治疗子宫肌瘤中的临床治疗效果。方法：随机选取2015年1月一2016年1月于我院就诊的子宫肌瘤患者98例，随机分为观察组(n=49)与对照组(n=49),观察组患者采用米非司酮联合桂枝茯苓胶囊进行治疗，对照组患者则仅使用米非司酮治疗，对比两组患者的治疗效果。结果：治疗前两组患者的子宫体积、肌瘤体积对比差异不显著，无统计学意义(P>0.05)；治疗后两组患者的子宫体积、肌瘤体积显著小于治疗前(P<0.05)；且治疗后观

2、察组患者的子宫体积、肌瘤体积显著小于对照组(P〈0.05)；治疗后观察组患者E2、P水平显著低于对照组(P<0.05)；观察组痊愈30例；显效9例；有效7例，无效3例；观察组治疗总有效率93.88%；对照组痊愈21例；显效10例；有效9例，无效9例；对照组治疗总有效率81.63%；观察组患者的治疗效果显著优于对照组(P〈0・05)。结论：采用米非司酮联合桂枝茯苓胶囊治疗子宫肌瘤，能够明显缩小子宫肌瘤的体积，治疗效果良好，具体临床推广价值。关键词：米非司酮；桂枝茯苓胶囊；子宫肌瘤中；临床疗效Toobservethecurativeeffe

3、ctofmifepristonecombinedwithGuizhifulingcapsuleinthetreatmentofuterinefibroids.Abstract:Objective:ToinvestigatetheclinicaltherapeuticeffectofmifepristonecombinedwithGuizhifulingcapsuleinthetreatmentofuterinefibroids.Methods:98patientswithuterineleiomyomawererandomlyselec

4、tedfromJanuary2015toJanuary2016inourhospitalwererandomlydividedintoobservationgroup(n=49)andcontrolgroup(n=49),theobservationgroupwastreatedwithmifepristonecombinedwithGuizhifulingcapsulefortreatment,wereonlymifepristonetreatmentgrouppatients,comparedtwogroupsofpatients.

5、Results:beforetreatment,thevolumeofuterinefibroidvolumedifferencesbetweenthetwogroupswasnotsignificant,nostatisticalsignificanee(P>0.05);afterthetreatmentofuterinevolume,tumorvolumeoftwogroupsofpatientswassignificantlylowerthanbeforetreatment(P<0.05);andaftertreatmentint

6、heobservationgroup,thevolumeofuterinefibroidvolumeweresignificantlylessthanthecontrolgroup(P<0.05);aftertreatment,thepatientsintheobservationgroupE2andPweresignificantlylowerthanthecontrolgroup(P<0.05);30caseswerecured;9casesweremarkedlyeffective;7caseswereeffective,3cas

7、esineffective;thetotalefficiencyoftheobservationgroup93.88%;controlgroup21caseswerecured;10casesweremarkedlyeffective;9caseswereeffective,9casesineffective;thetreatmentofthecontrolgroupthetotalefficiencyof8L63%;thetreatmenteffectofthepatientsintheobservationgroupweresign

8、ificantlybetterthanthecontrolgroup(P<0.05).Conclusion:UsingmifepristonecombinedwithGuizhifulingcapsulei