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1、-------AnalysisofRelationshipbetweenambulatorybloodpressurewithCAVIandABIchangeinhighbloodpressurewithtype2diabetespatientsAbstractObjectiveToinvestigatetheanalysisofrelationshipbetween24hambulatorybloodpressurewitharterialstiffnessindex:heart-anklevascularin
2、dex(cardio-anklevascularindex,CAVI),anklearmbloodpressureindex(ankle-brachialindex,ABI)changeinessentialhypertension(essentialhypertension,EH)withtype2diabetes(type2diabetesmellitus,T2DM)patients.Methods90caseshospitalizedpatientswererandomlydividedintotwogro
3、ups.47casesconsistedofhighbloodpressuregroup,andhighbioodpressuregroupassociatedwithdiabetesmellitusgroupincluding43cases.Everypatientwasmeasuredby24-hourambulatorybloodpressuremonitor,CAVI,ABIandcarotidultrasound.Every25patientswererandomlyselectedfromthetwo
4、groups.Thelevelsofserummalondialdehyde(MDA)weremeasuredusingthethibabituricAcid.Result(1)Fastingbloodglucose,C-reactionproteinlevel,carotidplaquesdetectionrateandserummalondialdehydeofEH+T2DMpatientsgroupweresignificantlyhigherthan-----------thoseofEHgroupres
5、pectively(P<0.05).(2)Theaverageineachperiodofsystolicbloodpressure(SBP),pulsepressure(PP),systolicbloodpressureload(SBP-L),earlymorningbloodpressure,systolicbloodpressurestandarddeviation(SBP-SD)andCAVIofEH+T2DMpatientsgroupweresignificantlyhigherandABIandnig
6、httimebloodpressureweresignificantlylowerthanthoseofEHgrouprespectively(P<0.05).4-----------AtthesametimeEHgroupinbloodpressurecurveoftypewas42.5%,EH+T2DMbloodpressurecurveofatypewas23.3%.(3)CAVIandSBP,PP,nSBP-L,nDBP-L,nSBP-SDwaspositivelyrelated(P<0.05orP<0.
7、01),R-ABIandSBP,dPP,SBP-L,dSBP-SDwasnegativelyrelated(P<0.05orP<0.01).L-ABIand24hSBP,nSBP,24hPP,dPP,SBP-L,dSBP-SDwasnegativelyrelated(P<0.05orP<0.01).ConclusionFordiabeticpatientswithhighbloodpressure,theaveragesystolicbloodpressure,pulsepressureload,systolic
8、bloodpressureandsystolicbloodpressureincreasedthathadapositivelyrelationwithCAVIandanegativecorrelationwithABI.Atthesametimethecircadianrhythmsweakened,earlymorningbloodpressureincreaseda
