光纤倏逝波生物传感器系统研究硕士学位论文

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1、中南大学硕士学位论文光纤倏逝波生物传感器系统研究姓名：李维申请学位级别：硕士专业：物理电子学指导教师：许雪梅20080521硕+学位论文ABSTRACTEvanescentwave．basedopticalfiberbiosensorsiSanimportantbranchofbiosensor,ithas30yearsofdevelopmenthistory．Becauseofitsuniqueadvantages，ithasgreatpotentialforapplicationintermsofwaterqualitymonitoring，foodhygieneinspec

2、tion，detectionofbiologicalwarfareagents．Inthispaperdetectionandprocessingsystemsisbuild，basedonthestudyoftheprincipleandthebasicstructureoftheEvanescentwave-basedopticalfiberbiosensor．Becauseoftheweakfluorescencesignalfromprobewhichaccompanyingwiththestronglasersignalandsystemnoise，SOhowtoext

3、ractaweakfluorescentsignalfromthestrongnoiseiscriticaltothewholesystem．Inordertosolvetheproblem，weworkintwoaspects．Inonhand，theprobestructureisdesignbyusinggeometricalopticsmethod，throughacombinationofEvanescentwavetheoryandpatternmatchingtheory．Itcanimprovetheefficiencyoftheprobe．Ontheotherh

4、and，becauseofthemorediscretecomponentsandhighsystemnoiseintraditionalevanescentwave—basedopticalfiberbiosensors，webuildaplatformbasedonFPGA+LabVIEW．Anon—chipsystemiSbuild．theA／Dsampling，signalgeneratorDDSandUARTinterfacearecontrolbyNiosIIsoft—coremicroprocessor．Thesystemthatincludingdataacqui

5、sition，datatransmission，modulationsignalintegrated，greatlyreducedthenumberofdiscretecomponentssystem，improvethesystemintegrationandSNR．Anapplicationsoftwaveprovidingsignaldetectionbydigitallock—inamplifier．datacommunicationwithFPGAandInterfacedisplayisbuildedbyusingLabVIEW．Finally，theexperime

6、ntiscarriedonafterbuildingtheEvanescentwave-basedopticalfiberbiosensors．Theexperimentalresultsshowthatthesystemsensitivityreachtolnmol／LwhendetecttheCy5solution．Thisbiosensorscanuseintheactualdetectionofbiologicalmaterialinhighprecisionapplicationrequirements．Thissystemhaslong—termstability,s

7、mallvolumeandsimplestructurewhichmakeitsuitableforlI硕十学位论文ABSTRACTfiledwork．KEYWORDS：fiberevanescentwave，digitallock—inamplifier,SOPC，LabVIEW111原创性声明本人声明，所呈交的学位论文是本人在导师指导下进行的研究工作及取得的研究成果。尽我所知，除了论文中特别加以标注和致谢的地方外，论文中不包含其他人已经发表或撰写过的研究成果，也不包含为获得中