“瘀”、“毒”从化——心脑血管血栓性疾病病因病机论文

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1、“瘀”、“毒”从化——心脑血管血栓性疾病病因病机论文史大卓,徐浩,殷惠军,张京春,陈可冀【摘要】心脑血管血栓性疾病发病过程中的血小板活化、黏附、聚集和血栓形成，传统中医药学多将其病因病机归于“血脉瘀阻”的范畴；但组织坏死、过氧化应激损伤、炎症反应等病理改变，远非单一“血瘀”病因所能概括。根据传统中医“毒”邪病因的认识，心脑血管血栓性疾病发病当存在“毒”邪致病或“瘀”、“毒”从化互结致病的病因病机。注重“瘀”、“毒”病因在心脑血管血栓性疾病发病过程中的相互兼夹、相互从化，探索中医治法方药，对丰富心脑血管血栓性疾病的中医病因学，提高临床疗效，具有重要意义。【

2、关键词】心血管疾病;血栓形成;血瘀Abstract:AccordingtothebasictheoryoftraditionalChinesemedicine(TCM),thepathogeicfactorssuchasplateletactivation,adhesion,congregationandthrombosisfallintothecategoryofbloodstasis,mation,etc,arefarbeyondtheetiologicalcategoryofbloodstasis.Thetoxinorthebinationandt

3、ransformationoftoxinandbloodstasisofTCMareinvolvedinthepathogenesisofthromboticcerebrocardiovascualrdiseases.ItissignificanttorecognizeandstressthebinationandtransformationoftoxinandstasisinpathogenicitysoastoenrichTCMetiologyandimproveTCMclinicalefficacyinthetreatmentofcerebroca

4、rdiovascularandthromboticdiseases.Keybosis;bloodstasis传统中医病因学.freeleandactivatingbloodcirculation.ZhongguoZhongXiYiJieHeXinNaoXueGuanBingZaZhi.2005;3(1):12.Chinese.陈可冀,李连达,翁维良,等.血瘀证与活血化瘀研究.中国中西医结合心脑血管病杂志.2005;3(1):12.2LiPT,edicalPublishingHouse.2004:15.Chinese.池明宇.中西医结合血栓病学.北京

5、:人民卫生出版社.2004:15.4.Plateletsinatherothrombosis.NatMed.2002;8(11):12271234.6PearsonTA,MensahGA,AlexanderRarkersofinflammationandcardiovasculardisease:applicationtoclinicalandpublichealthpractice:AstatementforhealthcareprofessionalsfromtheCentersforDiseaseControlandPreventionandt

6、heAmericanHeartAssociation.Circulation.2003;107(3):499511.7KovanenPT,KaartinenM,PaavonenT.Infiltratesofactivatedmastcellsatthesiteofcoronaryatheromatouserosionorruptureinmyocardialinfarction.Circulation.1995;92(5):10841088.8FeinbloomD,BauerKA.Assessmentofhemostaticriskfactorsin

7、predictingarterialthromboticevents.ArteriosclerThrombVascBiol.2005;25(10):20432053.9LiJZ.Attentiontoarterialthromboticdiseases.ZhonghuaNeiKeZaZhi.2006;45(1):23.Chinese.李家增.关注动脉血栓栓塞性疾病.中华内科杂志.2006;45(1):23.10PorterTR,LiS,OsterR,etal.Theclinicalimplicationsofnorefloonstratedicro

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