颈部淋巴结病变的ct灌注研究

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1、硕士学饭论文StudyofCTperfusionofCervicalLymphNodesName：TaULiliSupervisor：QiuShijunABSTRACTPartone：StudyoftheMethodforCTperfusionofCervicalTissueslISSUes[Objective]ToexplorethemethodforCTperfusionofcervicaltissues．[MeterialsandMethods]1、Subjects30patientswithnormalcervicalmusclesinNanfangHospital

2、underwentCTperfusionscanduringMay2007toMarch2008，inwhichl7weremaleand13werefemaIe。2、Equipmentandcontrastmedium(1)GElightspeedmulti--detectorrowscanner．(2)KMP810Phighpressuresyringe(Medradcorp．)．(3)Nonioniciodinatedcontrastagent，300mgI／m1．3、ExaminationtechniqueAxialscanrangedfrombaseofskull

3、tothelevelofsupraclavicularfossa,inwhichthescanparametersincluded5mmslicethickness，pitch1．375，120Kvand120～180mA．ABSTRACTTherangeofinterestformeasuringperfusionwascenteredonthelargestareaofnormalcervicalmuscles(wechoserightsternomastoidmuscleastheROIthistime)identifiedonthenon-contrastlocal

4、izingimages．Fouradjacent，5-mmsliceswereselectedatthelevelofthetumor．Fortymillilitersofnonioniccontrast(300mgI／m1)wereinjectedat4ml／s．At5secondsintotheinjection，acine(continuous)acquisitionwasinitiatedusingthefollowingparameters：120Kv,60mA，4×5mm，1-secondrotationand1-secondintervalforadurati

5、onof85seconds．4、DataprocessingandimagingevaluationTheperfusiondatawaspostprocessedusingcommerciallyavailablePerfusion3softwarepackageonGEADW4．2workstation．Aregionofinterestwasplacedinthefightinternalcarotidarteryandleftintemalcarotidarteryintum，exportinthefightsternomastoidmusclestogenerat

6、etime—densitycurvebycontrastenhancement．Someperfusionparametersweregeneratedautomatically，includingbloodflow(BF)，bloodvolume(BV)，meantransittime(MTT)andpermeabilitysurfaceareaproduct(PS)。Onthebasisofdifferemtinputarteriestheresultsweredividedintotwogroups-thegroupofri曲tinteralcarotidartery

7、andthegroupofleftinteralcarotidartery．一5StatisticalMethodForeachoftheperfusionparameters(BF、BV、MTTandPS)，wecomparedmeasurementsbetweenthegroupofrightinteralcarotidarteryandthegroupofleftinteralcarotidartery．Todetermineastatisticallysignificantdifferencebetween