银翘清心颗粒治疗小儿病毒性心肌炎（风热犯心证）的临床观察

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1、授予单位代码10089学号或申请号20152397中国图书分类号R272HebeiMedicalUniversity硕士学位论文学术是学位银翘清心颗粒治疗小儿病毒性心肌炎（风热犯心证）的临床观察研究生：周娟娟导师：黄春霞教授专业：中西医结合临床二级学院：河北省中医院2018年3月目录中文摘要··········································································································1英文摘要······································

2、····································································3研究论文银翘清心颗粒治疗小儿病毒性心肌炎（风热犯心证）的临床观察前言·········································································································6材料与方法·················································································

3、············6结果········································································································13附表········································································································14讨论································································

4、········································18结论········································································································24参考文献································································································24综述小儿病毒性心肌炎的中西医治疗研究概况·······················

5、·············27致谢················································································································37个人简历········································································································38中文摘要银翘清心颗粒治疗小儿病毒性心肌炎（风热犯心证）的临床观察摘要目的：研究自拟银翘清心颗粒治疗小儿病毒性

6、心肌炎（风热犯心证[1]）的临床疗效及安全性。方法：选取2016年3月~2017年12月期间就诊于河北省中医院儿科门诊患儿为研究对象，将60例符合纳入标准的病毒性心肌炎患儿，用随机数字表法分为2组，每组30例。对照组：注射用维生素C、注射用磷酸肌酸钠、热毒宁注射液分别加入5%葡萄糖注射液静脉滴注治疗。观察组：在对照组基础上加用中药银翘清心颗粒口服（采用免煎颗粒制剂，每日1剂，早晚分服）。疗程均为10天。观察治疗前后两组患儿临床症状、体征、心肌酶、心肌肌钙蛋白I及心电图的改善情况，运用统计学进行比较分析，用以评价临床疗效。结果：1.疗效比较治疗后，观察组中医证候改善总有效率为96.67

7、%，对照组为76.67%，两者相比较，有显著性差异(P<0.05)；在心悸、胸闷胸痛、咽痛、咳嗽咳痰、舌象及退热时间方面，观察组疗效均优于对照组(P<0.05)；在乏力、头晕方面，两组间无显著性差异(P>0.05)。2.两组心肌酶谱及心肌肌钙蛋白I比较治疗后，两组心肌酶及心肌肌钙蛋白I水平较治疗前均有明显下降(P<0.05)，观察组疗效优于对照组(P<0.05)。3.两组心电图比较治疗后，观察组ST-T改变、窦性心动过速和室性早搏治疗有效率分别为90.00