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时间:2018-10-29
《氧氟沙星和哌拉西林钠他唑巴坦钠联合应用在55例重症肺炎中的疗效3》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、氧氟沙星联合哌拉西林钠他哇巴坦钠治疗重症肺炎55例效果分析劳可柳作者单位:535400广西,灵山县人民医院重症医学科作者简介:劳可柳(1976-),男,大学本科,学士学位,主治医师,研究方向:重症医学。E-mail:77189615@qq.com电话:13977715156I摘要1目的探讨氧氟沙星联合哌拉丙林钠他唑巴坦钠治疗重症肺炎(SP)的疗效。方法110例SP患者采用随机数字表法分为观察组(n=55)及对照组(n=55)。对照组给予哌拉丙林钠他唑巴坦钠治疗,观察组给予氧氟沙星与哌拉西林钠他唑巴坦钠治疗,疗程均为10天。比较两组的临床疗效。结果观察组的发热消失、痰液
2、颜色正常、血常规恢复正常、胸部阴影吸收时间明显小于对照组(均P<0.05);治疗后,观察组WBC明®低于对照组(P<0.05),而PaO2、PaCO2高于对照组患者(均P<0.05);观察组临床疗效优于对照组(P<0.01);与治疗前相比,两组治疗后肝功能指标(ALT、AST)、肾功能指标(BUN、Cr)差异无统计学意义(P>0.05)。结论采用氧氟沙星联合哌拉两林钠他唑巴坦钠治疗重症肺炎效果满意,对肝肾功能无明S影响,值得推广。[关键词]重症肺炎;氧氟沙星;哌拉西林钠他唑巴坦钠;临床疗效[屮图分类号]R563.1[文献标识码][文章编号]1674-3806(2014
3、)00-0000-00doi:10.3969/j.issn.1674-3806.2014.00.00EffectofOfloxacinCombinedwithPiperacillinSodiumandTazobactamSodiumintreatmentofseverepneumonia:analysiof55casesLaoKeliu(Intensivecareunit,PeopledHospitalofLingshancounty,Guangxi,China,535400)[AbstractJObjectiveToinvestigateeffectofofloxa
4、cincombinedwithpiperacillinsodiumandtazobactamsodiumintreatmentofseverepneumonia(SP).Methods110patientswithSPwereselectedandrandomlydividedintotwogroups.Thecontrolgroupwastreatedwithpiperacillinsodiumandtazobactamsodium.Theobservationgroupwastreatedwithpiperacillinsodiumandtazobactamsod
5、iumcombinedwithofloxacin.Theclinicalefficacyofthetwogroupswerecompared.ResultsTheclinicalsymptoms,signsandlaboratorytest,mechanicalventilation,sputum,bloodtest,chestX-raywereinobservationgroupsignificantlylessthanthoseinthecontrolgroup(P<0.05).Aftertreatment,theWBCcountintheobservationg
6、roupwassignificantlylowerthanthatincontrolgroup(P<0.05).BothPaC)2andPaCC)2intheobservationgroupwerehigherthanthoseinthecontrolgroup(P<0.05).Thcefficacyoftheobservationgroupwasbetterthanthatofthecontrolgroup(P<0.05).Aftertreatment,ALT,AST,BUN,Crhadnosignificantdifferencebetweenthetwogrou
7、pscomparedwithbeforetrcatmcnt(P>0.05).ConclusionCombinationofofloxacinandpiperacillinsodiumandtazobactamsodiumintreatmentofseverepneumoniahasasatisfactoryeffect,andnoobviousadversereactionisobservedonliverandkidneyfunctions.[Keywords]Severepneumonia;Ofloxacin;Piperacillinsodium
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