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1、糖皮质激素长程应用患者药学干预作用分析(陕丙省延安市人民医院陕丙延安716000)【摘要】目的:探究糖皮质激素长程应用患者药学干预作用。方法:选取2013年3月〜2015年3月我院收治的90例原发性肾病综合征以及狼疮性肾炎患者作为研究对象,按照患者的入院顺序分为实验组和对照组,每组45例,给予实验组患者药学干预,未给予对照组患者药学干预,对比两组患者的药物依从性、糖尿病以及骨质疏松发生率、治疗效果。结果:对照组患者的药物依从性与实验组相比,差异只有统计学意义(P值<0.05),对照组患者的不良反应发生率为64.44%,显著高于实验组24.44%,组间差异具有统计学意义(P值均<0.05),实验
2、组患者的治疗效果与对照组相比,差异不明显,不具有统计学意义(P〉0.05)。结论:对糖皮质激素长程应用患者实施药学干预,患者对疾病的认识以及用药依从性得到有效提升,不良反应发生率减少,只有较高的临床应用价值。【关键词】糖皮质激素;药学干预;作用;分析【中图分类号】R969.3【文献标识码】A【文章编号】1004-6194(2015)02-0082-02Pharmaceuticalinterventioninpatientswithglucocorticoidlong-rangeapplicationeffectanalysisXiao-longguoZhangXiJunWangJuanShaa
3、nxiprovincepeople’shospitalZipcode:716000【Abstract】Oobjective:Toexplorethepatientswithglucocorticoidlong-rangeapplicationspharmaceuticalinterventioneffect.Methods:March2013〜March2015,ourhospital90casesofprimarynephroticsyndromeandwithlupusnephritispatientsastheresearchobject,accordingtothepatientsad
4、missionsequenceisdividedintotheexperimentalgroupandcontrolgroup,45casesineachgroup,experimentalgrouppatients1pharmaceuticalintervention,tocontrolpatientspharmaceuticalintervention,comparedtwogroupsofpatientstheincidenceofdrugcompliance,diabetesandosteoporosis,treatmenteffect.Results:Thedrugcomplianc
5、eofpatientswithcontrolgroup,experimentalgroupcomparedwithstatisticallysignificantdifference(Pvalues<0.05),theincidenceofadversereactionswas64.44%,controlgrouppatientswassignificantlyhigherthanthatoftheexperimentalgroupwas24.44%,statisticallysignificantdifferencebetweengroup(P<0.05),thetherapeu
6、ticeffectoftheexperimentalgrouppatientscomparedwithcontrolgroup,thedifferenceisnotobvious,notstatisticallysignificant(P>0.05).Conclusions:Inpatientswithglucocorticoidlong-rangeapplications,pharmaceuticalinterventionpatientsunderstandingofdiseaseandmedicationadherenceeffectively,reducetheincidence
7、ofadversereactions,hashighclinicalvalue.【Keywords】Glucocorticoid;Apharmaceuticalintervention;Role;Analysisofthe糖皮质激素属于逛体激素,来源于肾上腺皮质分泌,冋吋利用化学方法人工合成也能够形成[1]。生理剂量糖皮质激素能够对糖、脂肪以及蛋白质代谢造成一定影响,能够对水以及电解质代谢进行奋效