ct在难治性癫痫治疗中的综合应用

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1、CT在难治性癫痫治疗中的综合应用［摘要］目的探讨CT在难治性癫痫治疗中的应用。方法将1189例癫痫患者均应用常规的抗癫痫药物系统治疗6个月，将其中符合难治性癫痫诊断的160例，从中随机选取80例患者全部进行CT螺旋扫描，依据CT扫描结果，将CT阳性结果的患者分为A组，阴性患者分为B组，其余80例患者作为C组。A、B两组患者除继续应用常规一线抗癲痫药物治疗外，均联合应用其他不同的治疗方法，其中A组患者辅助低频重复经颅刺激和维生素E治疗，B组患者则加服中药及维生素E治疗，C组继续应用常规一线抗癲痫药物治疗。12个月后再对三组患者的疗

2、效进行评估。结果A、B两组患者经过12个月的联合治疗，A组的有效率为74.6%，B组的有效率80.0%，与联合治疗前疗效有较明显的提高。C组的有效率为40.0%。结论CT在探讨难治性癲痫的病因中有着重要作用，对其治疗方案的制定起着重要的指导作用。［关键词］CT;难治性癫痫；抗痫药治疗；中药治疗；低频重复经颅刺激［中图分类号］R742.1［文献标识码］B［文章编号］1673-9701(2015)25-0059-03ComprehensiveapplicationofCTintreatmentofrefractoryepilepsy

3、PANBinghuaWANGAiwuLENGXiaobingLIYumeiXIEXinyuanWANGXiangYichunThirdPeople’sHospital,Yichun336000，China[Abstract]ObjectiveToevaluatetheapplicationvalueofCTinthetreatmentofrefractoryepilepsy.Methods1189patientswithepilepsyweregivenconventionalantiepilepticdrugsystemati

4、ctreatmentfor6months.Amongthem，160patientsmettherefractoryepilepsydiagnosis,ofwhich80patientswererandomlyselectedtoreceiveCTspiralscanning,andbasedontheCTscanningresults,thepatientswithpositiveCTresultswereassignedtogroupAandthosewithnegativeCTresultswereassignedtogr

5、oupB,andtherest80patientswereassignedtogroupC.Inadditiontothecontinuousapplicationofconventionalfirst-lineantiepilepticdrugs,bothgroupAandgroupBweregiventhecombinedapplicationofotherdifferenttreatmentmethods.GroupAwasassistedwithlowfrequencyrepetitivetranscranialstim

6、ulationandvitaminEtreatment；groupBwasgivenadditionaloraladministrationoftraditionalChinesemedicineandvitaminEtreatment；groupCwasgiventhecontinuousapplicationofconventionalfirst-lineantiepilepticdrugs.Twelvemonthslater,efficacyofthethreegroupswasevaluated.ResultsAfter

7、12monthsofcombinedtreatment,theeffectiverateofgroupAwas74.6%andthatofgroupBwas80.0%,andtheefficacyofbothgroupsimprovedsignificantlycomparedtothatbeforethecombinationtreatment.TheeffectiverateofgroupCwas40.0%.ConclusionCTplaysanimportantroleinascertainingthepathogenes

8、isofrefractoryepilepsyandhasimportantguidingeffectonthedevelopmentoftreatmentprograms.[Keywords]CT；Refractoryepilepsy；Antiepileptic