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1、读书报告,英文 硕士研究生读书报告 姓名:郜志栋 学科、专业:研究方向:指导教师: 20xx年12月12日 AdvancesinthetranscriptionalregulationoftheflavonoidbiosyntheticpathwayAbstract:Flavonoidsaresecondarymetabolitesinvolvedinseveralaspectsofplantdevelopmentanddefence.Theycolourfruitsandflowers,favouring
2、seedandpollendispersal,andcontributetoplantadaptationtoenvironmentalconditionssuchascoldorUVstresses,andpathogenattacks.Becausetheyaffectthequalityofflowers(forhorticulture),fruitsandvegetables,andtheirderivatives(colour,aroma,stringency,etc.),flavonoidshaveahigh
3、economicvalue.Furthermore,thesecompoundspossesspharmaceuticalpropertiesextremelyattractiveforhumanhealth.Thankstoeasilydetectablemutantphenotypes,suchasmodificationofpetalpigmentationandseedsexhibitingtransparenttesta,theenzymesinvolvedintheflavonoidbiosyntheticp
4、athwayhavebeencharacterizedinseveralplantspecies.Conservedfeaturesaswellasspecificdifferenceshavebeendescribed.Regulationofstructuralgeneexpressionappearstightlyorganizedinaspatialandtemporalwayduringplantdevelopment,andisorchestratedbyaternarycomplexinvolvingtra
5、nscriptionfactorsfromtheR2R3-MYB,basichelix–loop–helix(bHLH),andWD40classes.ThisMYB–bHLH–WD40(MBW)complexregulatesthegenesthatencodeenzymesspecificallyinvolvedinthelatestepsofthepathwayleadingtothebiosynthesisofanthocyaninsandcondensedtannins. Keywords:bHLH,flav
6、onoids,MYB,transcriptionfactors,WD40. Introduction Flavonoidcompoundsaresecondarymetaboliteswidelyaccumulatedinvascularplantsandtoalesserextentinmosses.Theyaccumulateinallorgansandtissues,atdifferentstagesofdevelopment,anddependingontheenvironmentalconditions.B
7、esidetheirmultiplerolesinplantdevelopmentandadaptationtotheenvironment,thesemoleculesareofmajorinterestforhumannutritionandhealth.Indeed,theycontributetotheorganolepticqualityofplant-derivedproducts(colour,taste,flavour,etc.),and,inaddition,theyhavebeenshowntobeb
8、eneficialtohumanhealthandinpreventionofcellageing.Ingrape(VitisviniferaL.)berriesforinstance,theflavonoidcompositionisessentialforwinequalityandconservation.Mo