不同来源菊花化学成分、抗炎作用及其机理的研究

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1、万方数据(P

2、；不同品种；化学成分；抗炎药效：比较；机理V1万方数据ABSTRACTThisstudywascarriedoutsystematicallytoinvestigatethedifferencesonchemicalconstituents，inorganicelements，anti-inflammatoryefficacyandmechanismofdifferentcultivarsofFloSChrysanthemi．providingsomescientificevidencesforcomprehensivelyevaluatingthequaliti

3、esofdifferentcultivarsofFlosChrysanthemiandfacilitatingfurtherrefinementandstandardizationofFlosChrysanthemi．L9(34)orthogonaldesignwasusedtooptimizetheextractiontechnologyofFlosChrysanthemi．Thebestextractiontechnologywasoptimizedwiththeinvestigatetarget，peakareaoftheeightmajorcomponen

4、toffingerprintinFlosChrysanthemiandthecontentofextractum．111eextractionprocesswasasfollows：ultrasonicextractionmethod，30一foldethanolof80％concentration，2timesforextraction，40minuteseachtime．Themethodisreasonable，feasibleandsignificanttOthespecificationofextractionprocessandqualitycontr

5、olofFlosChrysanthemi．TheresultsshowedthatthemainchemicalcompositionshadqualitativedifferencesindifferentcultivarsofFlosChrysanthemibyqualitativeanalysisoftheirHPLCfingerprints，UFLC—TOF／MSandGC—MS。ThroughtheestablishmentoftheHPLCfingerprintofdifferentcuRivarsofFlosChrysanthemiandthesim

6、ilarityanalysis，theclusteringanalysisandtheprincipalcomponentanalysis，theresultsshowedthathighsimilaritybetweenthesampleoftheSalTlebreed，fingerprintcommonmodelwasstable，reliableandstrongspecificity．Indifferentcultivars，130juandChujuhadhighsimilarity，GongjuandHangjualsohadhighsimilarit

7、yperhapsbecausetheymightcomefromthesalnespeciesrespectively．ThroughGC—MSqualitativeanalysis，156kindsofchemicalcomponentswereidentified，including70，58，58，61and76kindsofchemicalcomponentswereidentifiedinChuju，Boju，Gongiu，Huaiju，Hangju，respectively，allcultivarsoftheSalTlecomponemforl5kin

8、ds，an