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1、CMEONOSTEOMYELITIS8/3/2021PresentingBy-Dr.GolamMahmud(Suhash)From-DepartmentOfOrthopaedic&Traumatology,ShaheedSuhrawardyMedicalCollegeHospital,Dhaka.1Osteomyelitismaybedefinedasanacuteorchronicinflammatoryprocessofbone,bonemarrowanditsstructuresecondarytoinfectionwithmicroorgani
2、sms.DefinitionofOsteomyelitis:8/3/2021238/3/2021TheCierny-Maderstagingsystemisused.Itisdeterminedbythestatusofthediseaseprocessregardlessofitsaetiology,regionalityorchronicity.Ittakesintoaccountthestateofthebone,thepatient'soverallconditionandfactorsaffectingthedevelopmentofoste
3、omyelitis.StagingOfOsteomyelitis:48/3/20211:Medullaryosteomyelitis(infectionconfinedtothebonesurface)Stage.2:Superficialosteomyelitis(contiguoustypeofinfection)Stage.3:Localisedosteomyelitis(full-thicknesscorticalsequestrationwhichcaneasilyberemovedsurgically)Stage.4:Diffuseoste
4、omyelitis(lossofbonestability,evenaftersurgicaldebridement).AnatomicalStagingOfOsteomyelitis:InNewborns(youngerthan4mo)-S.aureus,Enterobacterspecies,andgroupAandBStreptococcusspeciesInChildren(aged4moto4y)-S.aureus,groupAStreptococcusspecies,Haemophilusinfluenzae,andEnterobacter
5、speciesInChildren,adolescents(aged4ytoadult)-S.aureus(80%),groupAStreptococcusspecies,H.influenzae,andEnterobacterspeciesInAdult-S.aureusandoccasionallyEnterobacterorStreptococcusspeciesInSickleCellAnemiaPatients-SalmonellaspeciesFungusalsocausesosteomyelitis.Etiologicalagents:8
6、/3/20215Hematogenous-commoninchildrenDirectinoculation(usuallytraumatic,butalsosurgical)Localinvasionfromacontiguousinfection(usuallydecubitusulcerorperiodontaldisease)Pathogenesis8/3/20216Hematogenousosteomyelitishighestinthefirsttwodecadesoflife.<5yearsofage.Inadult-Haematogen
7、ousislesscommonbuttheysufferedduetodebility,disease(diabetesmellitus)drugs(immunosuppresion).Pathogenesis(cont….)8/3/20217Discontinuousendotheliumofdistalmetaphysealvessels----passageofbacteriathroughthesegaps---depositionTraumaorembolileadtoocclusionoftheslow-flowingsinusoidalv
8、essels,furtherestablishinganidusforinfection.Me