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1、急性心肌梗死合并室间隔穿孔的近期预后因素付艳华(郑州大学公井卫生学院郑州大学第五附属医院河南郑州450052)【摘要】目的:探讨急性心肌梗死(AMI)合并室间隔穿孔(VSR)的近期预后因素。方法:选取并回顾性分析2005年1月一2014年5月于我院住院治疗的65例AMI合并VSR患者,根据患者发病后的存活期分为两组:S组(存活≤30d,34例)和L组(存活〉30d,31例),比较两组患者的年龄、性别构成比、病史及实验室检查结果,分析存活期≤30d的危险因素,采用Logistic多元回归分析方法,制定AMI合并VSR患
2、者的近期预后危险评分。结果:S组与L组临床指标比较结果显示,女性、Killip分级≥IIl级、前壁心梗、无室壁瘤形成、室间隔穿孔发生在近心尖部和AMI发作至VSR确诊的时间(AMI-VSR时间)≤4d等方面差异有统计学意义(P均<0.05)。Logistic多元回归分析结果显示,女性、Killip分级≥III级、前壁心梗、不合并糖尿病、无室壁瘤形成和AMI-VSR时间≤4d均为AMI合并VSR患者存活期≤30d的独立危险因素。结论:AMI合并VSR患者存活期≤30d的独立危险因素似括女性、Ki
3、llip分级≥III级、前壁心梗、不合并糖尿病、无室壁瘤形成及AMI-VSR时间≤4d,对具有高危因素的患者应给予更积极有效的治疗。【关键词】室间隔穿孔;心肌梗死;危险因素【中图分类号】R541【文献标识码】A【文章编号】2095-1752(2015)12-0077-02TherecentprognosticfactorsofacutemyocardialinfarctionmergerventricularseptalperforationFuYanhuaSchoolofPublicHealth,Zhengzhou
4、University;TheFifthAffiliatedHospitalofZhengzhouUniversity,He’nanProvince,Zhengzhou450052,China【Abstract】ObjectiveTostudytheacutemyocardialinfarction(AMI)withventricularseptalperforation(VSR)recentprognosticfactors.MethodsSelectionandretrospectiveanalysisinJanu
5、ary2005toMay2014inourhospitaltreatmentof65casesofAMIpatientswithcombinationofVSR.Accordingtopatientsafteronsetofsurvivaltimewasdividedintotwogroups:groupS(survival≤30d,34cases)andLgroup(survive>30d,31cases).Comparetwogroupsofpatientsage,gender,historyandlaborat
6、oryresults,usingLogisticmultivariateregressionanalysismethod,makingtherecentprognosisofpatientswithriskscore.ResultsComparisonresultsshowedthatwomen,KillipclassacuityIII,anteriorwallmyocardialinfarction,noaneurysmformation,ventricularseptalperforationoccurredinnearap
7、ex,andonsetofAMIandVSRdiagnosed(AMI-timeofVSR)aspectsandsoon4dorlessdifferencewasstatisticallysignificant(P<0.05).Logisticmultivariateregressionanalysisresultsshowedthatwomen,KillipclassacuityIII,anteriorwallmyocardialinfarction,diabetesmellitus,ventricularaneurys
8、mformationandAMI•VSRtime4dorlessaretheAMIpatientswithcombinationofVSRsurvivalacuitieswereindependentriskfactorsfor30d.ConclusionInc