消化性溃疡英文课件

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1、PepticUlcerDisease消化性溃疡病Question:What’sthemeaningof“PepticUlcerDisease”?DefinitionPepticUlcerDiseaseisdefinedasanulceroccurringinaregionthattouchesgastricacid(胃酸)andpepsin(胃蛋白酶)andusuallyreferstogastriculcer(胃溃疡)orduodenalulcer(十二指肠溃疡).Typicalendoscopicappearanceof

2、abenigngastriculcer.Theulcerisontheangularis,themostcommonlocationforagastriculcer,andiswellcircumscribedwithoutanyassociatedmasseffect.Thesurroundingmucosaismildlyerythematous红斑的andwithoutnodularity结节.Typicalradiographicfeaturesofabenigngastriculcer.Alargewell-cir

3、cumscribedulcerisseenontheangularis.aposteriorduodenalulcerTypicalradiographicfeaturesofduodenalulcer.Thisduodenalbulbulcerisassociatedwithmarkededema,resultingintheappearanceofradiatingfoldstotheulcercrater.Thebulbisalsodistoredsecondarytopreviouslyexistingulcerat

4、ion.Questions:Whatdoesulcer溃疡mean?Howcanwedifferentiatebetweenulceranderosion糜烂?ErosionsintheduodenalbulbandaposteriorduodenalulcerErosion糜烂:asuperficiallesioncausedbydenudationofthesurfaceepithelium（上皮细胞）ulcer溃疡:amucosaldefectextendingintothemuscularismucosa(粘膜肌层)

5、Mucosacanbedividedinto:Epithelium上皮Laminapropria固有层Muscularismucosae粘膜肌层ClinicalmanifestationsofPepticUlcerDiseases消化性溃疡病的临床表现symptoms症状abdominalpain腹痛locatedintheepigastric(上腹)area;burninginquality(烧灼样);occurredonanemptystomach2to4hoursaftermealsand/oratnight(noct

6、urnalpain夜间疼痛);relievedbyantacids(抗酸剂)and/ormeals(进餐);tendtowaxandwane(加重与缓解)overmonths“aciddyspepsia酸消化不良”themajorityofpatients(approximately70%)withepigastricdistress(“dyspepsia”)donothaveevidenceofactiveulcerdisease;converselyupto40%ofpatientswithanactiveulcercr

7、aterdenyabdominalpain;patientscanpresentwithanulcer-relatedcomplication,particularlyhemorrhage,withoutantecedentsymptomsdespitebeingbothinsensitiveandnon-specific,thesymptomofepigastricabdominalpain,particularlyburningaftermealsandatnightandrelievedwithfoodorantaci

8、d,suggeststhepossibilityofulcerdisease.Othersymptomsgastroesophagealreflux胃食管反流(includingupright直立位andsupine仰卧位refluxandnon-cardiacchestpain非心源性胸