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1、diabetesneuropathies:updateondefinitions,diagnosticcriteria,estimationofseverity,andtreatments糖尿病神经病变:更新的定义,诊断标准,估计的严重程度,与治疗TesfayeS,BoultonAJ.DyckPJ,etal.内容概要,博尔顿一·戴克磷,等。AbstractPrecedingthejointmeetingofthe19thannualDiabeticNeuropathyStudyGroupoftheEuropeanAssociationfortheStudyofD
2、iabetes(NEURODIAB)andthe8thInternationalSymposiumonDiabeticNeuropathyinToronto,Canada,13–18October2009,expertpanelswereconvenedtoprovideupdatesonclassification,definitions,diagnosticcriteria,andtreatmentsofdiabeticperipheralneuropathies(DPNs),autonomicneuropathy,painfulDPNs,andstruct
3、uralalterationsinDPNs.前联席会议第十九年糖尿病神经病变研究组欧洲糖尿病研究协会(neurodiab)和第八届国际糖尿病神经病变在多伦多,加拿大,–13182009年十月,专家小组召开了提供更新的定义,分类,诊断标准,治疗糖尿病周围神经病变(标准草案),自主神经病变,痛苦的标准草案,和结构改变的标准草案。CLASSIFICATIONANDDEFINITIONOFDIABETICNEUROPATHIES定义和分类糖尿病神经病变SolomonTesfaye,MD,FRCP,1AndrewJ.M.Boulton,MD,2PeterJ.Dyck,MD
4、,3RoyFreeman,MD,4MichaelHorowitz,MD,PHD,5PeterKempler,MD,PHD,6GiuseppeLauria,MD,7RayazA.Malik,MD,2VincenzaSpallone,MD,PHD,8AaronVinik,MD,PHD,9LucianoBernardi,MD,10PaulValensi,MD,11andonbehalfoftheTorontoDiabeticNeuropathyExpertGroup*所罗门内容概要,医学博士,联邦民事诉讼规则,1安得烈J.博尔顿,医学博士,2彼得·戴克,医学博士,医学
5、博士,43罗伊,迈克尔霍洛维茨,医学博士,博士,5彼得肯普勒,医学博士,博士,6家7rayaz朱塞佩,医学博士,马利克,医学博士,医学博士,博士2文森泽斯帕龙,,8亚伦vinik,医学博士,博士,9大卢西亚诺,医学博士,10保罗瓦朗西,博士,11代表多伦多糖尿病神经病变专家组CLASSIFICATIONANDDEFINITIONOFDIABETICNEUROPATHIESTheneuropathiesdevelopinginpatientswithdiabetesareknowntobeheterogenousbytheirsymptoms,patternofn
6、eurologicinvolvement,course,riskcovariates,pathologicalterations,andunderlyingmechanisms(1,2).Thomas(3)andBoultonetal.(4)separatedtheseintogeneralizedandfocal/multifocalvarieties(e.g.,multiplemononeuropathy,lumbosacral,thoracic,andcervicalradiculoplexusneuropathies)(3,4).Itisknowntha
7、tsimilarpatternsofneuropathyoccurinpatientswithoutdiabetes(2).Moreover,diabeticpatientscandevelopchronicinflammatorydemyelinatingpolyradiculopathy.Theevidencethatgeneralizedvarietiescanbefurtherclassifiedintoatleasttwomajorsubgroupsseemscompelling(3,4).ThetypicalDPNisachronic,symmetr
8、ical,length-