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1、老年2型糖尿病合并缺血性脑卒中的病变特点及危险因素分析钟菊佛山市第一人民医院同济康复医院内科广东佛山528000基金项目:佛山市卫生和计生局医学科研课题(编号20170179)【摘要】目的观察佛山地区糖尿病合并心血管病患者的临床特征,并分析其危险因素。方法选取2015年2月-2016年2月间佛山地区2型糖尿病患者1877例为研究对象,其中600例合并心血管病患者为观察组,1277例未合并心血管病患者为对照组,比较两组临床资料,并以Logistic多元回归分析2型糖尿病患者合并心血管病的危险因素。结果观察组包括心肌缺血102例,心绞痛121
2、例,心肌梗死98例,心律失常99例,高血压180例。观察组DM病程(10.3±3.1vs8.9±2.5)及吸烟年限(19.1±6.2vs16.5±6.6)长于对照组,BMI大于对照组(24.1±1.3vs23.3±1.1),存在脂肪肝(60.2%vs54.2)、脑血管病(56.2%vs50.4%)的比例高于对照组(P<0.05)。观察组TC、TG、FIB、FBG、2hPBG及HbA1C显著高于对照组,HDL及ApoA水平显著低于对照组(P<0.05)。糖尿病病程、HbA1C及吸烟年限是2型糖尿病合并心血管的独立危险因素(P<0.05)。结
3、论2型糖尿病合并心血管病的发生率高,随着糖尿病病程的延长、HbA1C控制不良、吸烟年限的延长,其发生心血管病的危险性增加。【关键词】2型糖尿病;心血管病;缺血性;Logistic分析Characteristicsandriskfactorsofischemicstrokeinelderlypatientswithtype2diabetesmellitusZhongJuDepartmentofinternalmedicine,Tongjirehabilitationhospital,firstpeople'sHospitalofFoshan
4、,Guangdong528000,Foshan,China[Abstract]ObjectiveToobservetheclinicalcharacteristicsofdiabetesmellituscomplicatedwithcardiovasculardiseaseinFoshan,Theriskfactorswereanalyzed.Methodsatotalof2patientswithtype1877diabetesmellitusinFoshanfromFebruary2015toFebruary-2016weresele
5、ctedasthesubjects,Amongthem,600patientswithcardiovasculardiseaseweretheobservationgroup,1277patientswithnocardiovasculardiseasewereincludedinthecontrolgroup,Theclinicaldataofthetwogroupswerecompared,Logisticregressionanalysiswasusedtoanalyzetheriskfactorsofcardiovasculard
6、iseaseintype2diabetesmellituspatients.Resultstheobservationgroupconsistedof102casesofmyocardialischemia,121casesofanginapectoris,98casesofmyocardialinfarction,99casesofarrhythmia,and180casesofhypertension.TheobservationgroupDMcourseofdisease(10.3±3.1vs8.9±2.5)andsmokingye
7、ars(19.1±6.2vs16.5±6.6)werelongerthanthecontrolgroup,BMIwasgreaterthanthatofthecontrolgroup(24.1±1.3vs23.3±1.1),Theproportionoffattyliver(60.2%vs54.2)andcerebrovasculardisease(56.2%vs50.4%)washigherthanthatofthecontrolgroup(P<0.05).ThelevelsofTC,TG,FIB,FBG,2hPBGandHbA1Cin
8、theobservationgroupweresignificantlyhigherthanthoseinthecontrolgroup,ThelevelsofHDLandApoAweresi