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1、运用腰池-腹腔分流术与脑室-腹腔分流术治疗交通性脑积液患者的Meta分析吕东钟东张福安李炯黄浩洋杜伟夏海坚重庆医科大学附属第一医院神经外科摘要:目的探讨脑室-腹腔(V-P)和腰池-腹腔(L-P)分流术治疗交通性脑积水患者的疗效。方法采用计算机检索PubMcdxWebofScience、Scopuss、Karger、EBSCO+MEDLINE、OVID、EMBASE、中国知网、中国生物医学全文库、万方、维普数据库,查出1990-2016年上述数据库所收录的有关L-P和V-P分流术治疗交通性脑积液的相关文献,并运用STATA12.0软件进行Me
2、ta分析。结果交通性脑积液患者予以L-P分流手术的成功率明显高于V-P分流术(P〈0.05),术后感染率、分流系统梗阻率及总并发症发生率较低(P<0.05),两组的分流欠佳率差异无统计学意义(P〉0.05)。结论L-P分流术在交通性脑积液患者中值得推荐,由于证据质量较低,需要更多高质量的原始研宄来弥补该研宄的不足。关键词:交通性脑积液;腰池-腹腔分流术;脑室-腹腔分流术;Meta分析;作者简介:吕东(1989-),硕士,主耍从事神经外科工作。作者简介:钟东,E-mail:zhongdongdp@sina.com。收稿日期:2017-05-0
3、4基金:国家临床重点专科建设项0(财社[2011]170号)Applicationoflumboperitonealshuntandventriculoperitonealshuntintreatmentofpatientswithcommunicatinghydrocephalus:aMetaanalysisLyuDongZhongDongZhangFuanLiTiongHuangHaoyangDuWeiXiaHaijianDepartmentofNeurosurgery,FirstAffiliatedHospitalofChongqin
4、gMedicalUniversity;Abstract:ObjectiveToinvestigatetheeffectoflumboperitoneal(L-P)shuntanclventriculoperitoneal(V-P)shuntfortreatingthepatientswithcommunicatinghydrocephalus.MethodsThedatabasesofPubMed,WebofScience,Scopuss,Karge,EBSCO+MEDLINE,OVID,EMBASE,CNKI,CBMdiscdatabas
5、es,Wanfangdatabases,Weipudatabaseswereretrievedbycomputer.TherelevantliteraturesaboutL-PshuntandV-Pshuntfortreatingcommunicatinghydrocephalusincludedinthesedatabasesduring1990-2016werecollectedandperformedthemetaanalysisbyusingtheSTATA12.0software.ResultsThesuccessrateofL-
6、PshuntintreatingcommunicatinghydrocephaluswasapparentlyhigherthanthatofV-Pshunt(P<0.05).Moreover,postoperativeinfectionrate,obstructionrateofshuntsystemandtotalpostoperativecomplicationsrateinL-PshuntwereapparentlylowerthanthoseofV-Pshunt(P<0.05),However,therewasnostatisti
7、caldifferenceinshuntpoorratebetweenL-PshuntandV-Pshunt(P>0.05).ConclusionI厂Pshuntisworthrecommending.Butduetolowerqualityoftheevidences,itisneededmorehighqualityprimarystudiestoremedytheinsufficiencyofthestudy.Keyword:communicatinghydrocephalus;lumboperitonealshunt;ventric
8、uloperi-tonealshunt;Meta—analysis;Received:2017-05-04根据脑脊液循环动力学可将脑积液分为梗阻性脑积液和交通性脑积液。交通性脑积