儿童类风湿病复旦大学附属儿科医院课件

《儿童类风湿病复旦大学附属儿科医院课件》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、幼年特发性关节炎复旦大学风湿过敏免疫中心复旦大学附属儿科医院肾脏风湿科周利军fenlin183@yahoo.com.cnEvaluationonly.CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.0.Copyright2004-2011AsposePtyLtd.Introduction周四下午，风湿专科54524666转5084肾脏风湿科病房54524666转3011fenlin183@yahoo.com.cnEvaluationonly.CreatedwithAspose.Slidesfor.NET3.5ClientProfile

2、5.2.0.0.Copyright2004-2011AsposePtyLtd.幼年特发性关节炎（JIA)JuvenileIdiopathicArthritisJuvenileRheumaticArthritisJuvenileChronicArthritis2001,JIAhasbeenconfirmedbyILAREvaluationonly.CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.0.Copyright2004-2011AsposePtyLtd.TypesofAutoimmuneDiseaseEvaluationonly.

3、CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.0.Copyright2004-2011AsposePtyLtd.幼年特发性关节炎（JIA)16岁以下儿童长期发热、皮疹淋巴结和肝脾肿大胸膜炎和心包炎反复发作可致关节畸形Evaluationonly.CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.0.Copyright2004-2011AsposePtyLtd.幼年特发性关节炎（JIA)3岁男孩，弛张热，肝脾肿大少量心包积液、充血性随热出现皮疹疾病？？？Evaluationonl

4、y.CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.0.Copyright2004-2011AsposePtyLtd.病因和发病机理感染遗传1979StastyFinkHLA-DW7,DW8寒冷潮湿疲劳营养不良Evaluationonly.CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.0.Copyright2004-2011AsposePtyLtd.病因和发病机理Evaluationonly.CreatedwithAspose.Slidesfor.NET3.5Client

5、Profile5.2.0.0.Copyright2004-2011AsposePtyLtd.病理变化关节病变皮下结节眼部病变其他Evaluationonly.CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.0.Copyright2004-2011AsposePtyLtd.免疫异常和损伤依据血IgGIgAIgM不同程度升高部分患儿补体升高可出现血和关节液RF阳性血和关节液TNF水平增高迟发超敏反应降低Evaluationonly.CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.

6、0.Copyright2004-2011AsposePtyLtd.自身抗体的临床价值在典型风湿病—肯定诊断（A-dsDNA,ACL)在不典型风湿病—提示诊断如多关节炎(CCP抗体阳性)评估预后及指导用药抗体谱广+高滴度病情重用药规范Evaluationonly.CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.0.Copyright2004-2011AsposePtyLtd.自身抗体的临床价值Evaluationonly.CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.0.Co

7、pyright2004-2011AsposePtyLtd.新近JIA相关抗体抗CCP抗体BiP抗体AFA抗GPI抗体抗CB10抗体Evaluationonly.CreatedwithAspose.Slidesfor.NET3.5ClientProfile5.2.0.0.Copyright2004-2011AsposePtyLtd.临床表现　Manifestation全身型多关节,RF+多关节,RF-少关节,持