infectious disease虫媒传染病课件

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1、Vector-BorneInfectiousDiseaseDanielleKrugerLYME’SDISEASEETIOLOGY:BorreliaburgdorferilooselycoiledspirocheteLYME’SDISEASEVector:Ixodesscapularis:adultfemale,male,nymph,&larvaoncmscaleIxodiddeertickLYME’SDISEASEReservoir:White-footedmouseWhite-taileddeerLYME’SDISEASELocalizedrash:Erythe

2、mamigrans12-y/ogirlpresentedtoherPCPwitha6-cmcircleoferythemawithcentralclearingonthesideofherneck.ThepatientlivedinanareaofConnecticutwhereLymediseaseisendemic.Diagnosedwitherythemamigransandprescribedamoxicillin-after20daysofantibiotictherapy,therashhadenlargedandcontainedmultipleri

3、ngs.Thoughtshehaderythemamigransunresponsivetoamoxicillintherapy.Theeruptionwasmildlypruritic,andthepatienthadnoconstitutionalsymptoms.SeeninPediatricERWelearn–herfamilyapplyingahigh-potencytopicalsteroidtoherneckprescribedforsomeoneelseKOHprep:fungalhyphaeFungalculture:TrichophytonBe

4、cognizantofdifferentials:erythemamigransisrarelyscalyandresolvesrapidlywithappropriateoralantibiotictherapy(amoxicillinordoxycycline)."Tineaincognito"-tineainfectionmodifiedbytopicalsteroids;suppresslocalimmuneresponseallowingfungustogroweasily-bizarreappearance!LYME’SDISEASEROCKYMOUN

5、TAINSPOTTEDFEVERThemostsevereandmostfrequentlyreportedrickettsialillnessintheUnitedStates.verysmallbacteriumthatmustliveinsidethecellsofitshostsRickettsiarickettsiiMicrobe:Vector:Dermacentortick(Americandogtick)TypicalpetechialrashJustforComparison…Dermacentortick(Americandogtick)Ixod

6、iddeerticksTULAREMIAMicrobe:TULAREMIAVector:UlceratinglymphadenitisOcularglandularUlceroglandularCATSCRATCHDISEASEMicrobe:BartonellahenselaeVector:CATSCRATCHDISEASELocalizedpapule®ionallymphadenopathyMALARIAMicrobe:PlasmodiumfalciparumPlasmodiummalariaePlasmodiumvivaxPlasmodiumoval

7、eVector:AnophelesmosquitoMALARIATREATMENTLyme’sdisease:RockyMountainSpottedfever:Tularemia:CatScratchdisease:Malaria:Doxycycline,TetracyclineDoxycycline,TetracyclineStreptomycin,GentamicinZithromax,Cipro“Quines”