海绵状血管畸形英语病例讨论2012课件

海绵状血管畸形英语病例讨论2012课件

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时间:2018-10-02

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1、Casediscussion 2012-02-09DepartmentofRadiologyYangzhouNo.1people’sHospital26Y.Ofemalecomplainedseizureaccompaniedlossofconsciousness.normalPE.NoobviouslyabnormalhistoryCTCT:60HUFollowupMRI2weekslaterCEMRIfollowup4weekslaterFindingsCT:Rightfrontalsubcorticallesion.Heterogenoushighdensitymasswit

2、hmildmasseffectwithoutsurroundingedema.Anteriorhornoftherightventricularissuppressed.midlinestructuresshiftedleftMRT1WI:heterogenoushighSIlesionwithfocallowSIT2WI:heterogenouswithringoflowSICE:mildenhancementDSA:NoobviouslyabnormalvascularstructuresDDXAneurysmArteriovenousMalformationCapillary

3、TelangiectasiaHypertensiveHemorrhageMetastasesVenousVascularMalformationsCysticercosis,CNSGangliogliomaHemangioblastoma,BrainMeningiomaOligodendrogliomaTuberculomaCavernousMalformationsCavernousMalformationsadistinctpathologicsubtypeofvascularmalformation,appearingasahoneycombofendothelial-lin

4、edsinusoidalvascularspaceswhichcontainstagnantblood.angiographicallyoccultThrombosis,calcification,andhemorrhagearecommonbrainparenchymamaybeasymptomatic,seizuresarethemostcommonpresentingsymptomandoftennecessitatesurgeryCavernousMalformationsoccuranywhereintheCNSandaremultiplein1/3ofcasesSurr

5、oundingneuraltissuemaydemonstrategliosisaffectmalesgreaterthanfemalesandoccurbetweenthirdandsixthdecadeDiagnosis:CT,aswellas MRI,which isoftendiagnosticTreatment:Seizuresmaynecessitateaggressivesurgicalintervention. Otherwise,carefulobservationisindicated.RadiologyCT:extensivecalcifications=he

6、mangiomacalcificans(20%)smallroundhyperdenseregion(ifmalformationissolitary)nosurroundingedemaormasseffectRadiologyMRIWell-definedareaofmixedsignalintensitycentrally("mulberry-shaped"'lesion)Increasedsignalintensity:extracellularmet-hemoglobin,slowflow,andthrombosisDecreasedsignalintensity:deo

7、xy-hemoglobin,intracellularmet-hemoglobin,hemosiderin,calficicationsSurroundinghypointenserim(T2andFLAIR)=hemosiderinAngio:negative-"occultcerebrovascularmalformation,'OCVMPearlsCharacteristicT2WIfindingsofa well-defined"mulberry"lesion

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