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时间:2018-09-15
《抽吸法诱导兔椎间盘退变模型的病理及影像表现》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、万方数据中国组织工程研究与临床康复第f3誊勇争46勇汐2009—11—12出版J∞ma
2、ofclinlcalRehab{litativeTiSsueEngineenngRe∞arch№vember12.2009Ⅷ.13,No.46欠7;濯基础医学抽吸法诱导兔椎间盘退变模型的病理及影像表现水☆周松,李锋,陈安民,方忠,陈文坚,牛鹏彦PathoIogyandimagingperl-ormanceofrabbitintervertebra1discdegeneratIOnmodeIinducedbytheaspirationofnucIeuSpuIpOsusZhouS
3、ong,LiFeng,ChenAn—min.FangZhong,ChenWen.jian,NiuPeng—yanAbstractBACKGROUND:ThepathOgenesisofinteMrteb馆ldiscprotrusion怕mainsunclear.AstabIeandfeas.bIeinterverteb旧ldiscdegenera廿OnmOdeI.srequi呜dtoVaIid锄ethepathOIogyandimagingpe哟mlan∞andto怕V∞
4、tntemalfacto倦.OBJECTlVE:To;nvestigatethefeas.
5、b;ljty0fb训ding阳bbitmodeIofinterve^曲raIdjscdegene阳tionusingaspi陷t幻nme廿10d.aswe¨astheconvenienceandstabi¨tyofmodeIestabIishmentthroughtheperfbmlance0fpathologyandimaging.MATERlALS:Atotal0f4210-month_0ldheaIthyNewZeaIand怕bbits,inespedive0fgende阽,we限懵ndomIydividedintDcontrolgfoupandexpef
6、ime嗽groupw{蜘2'rabb缱s细铀chg∞up.Sumjanxjnwaso胞redbyVeterjnaryJn鲥tute,Quarte咖a鲫钟UniVers耐ofChinesePLA.nChangchunCity.ME.rHODS:Thedischeightindex(DHl)ofa¨阳bb№wassetasl00%.A21_gaugehypode丌.nicneedlewasusedtoaspi阳tenucIeuspuIposus8—12mgfromL4{discof怕bbitsIntheexperimentgroup,whiIecontmlgroup
7、怕ceiVednomanagemenL,U4,12.20weeks。7rabbltswereseIecfedfromeachgroupforindexdete丌T1ina“On.MAIN0UTCOMEMEASURES:DHIper∞nt,X.阳ypIain行Im,MRIandAIcianbIues协injngwe帕usedtoOb转rVethechangesintheinten,ertebraIdiscdegeneratiOn.RESuLTS:TheDHIpen∞ntageofexpenmentgroupat4,12and20w∞ks怕spedivelywas(
8、81.0±3.2)%,(75.0±2.5)%and(71.O±1.8)%,withsignin∞ntd№rence∞mpa删tocontroIgroup(P《0.05).T2-weightedima9eshowedthatthesignal0fthediscswassigni订cantlydecreased,andA}cianbI∞stainingsho啪dthatthe∞ntentofagg陀canwasaIsosign撕cantlydecfeased.CoNCLU勒0N:Theaspi旧aOnisa怕Iiableandconvenientwayto∞nstr
9、uct怕bbitmOdeIsofintervert曲旧Idiscdegene怕nOn,andthesemOdelsexhjbitthesimIIarpathOIOgyandimagingpe哟n_nan∞w.thhumaninterverteb佑Idiscdegene懵tIOn.ZhouS。LiF,ChenAM,FangZ,Ch骱wJ,NiuPY.PathOlOgyandjmagingpe巾佣an∞of偿bbjtinteMrteb旧ldiscdegenerati∞modeIindu∞dbytheaspifationofnucleuspuIposus.Zhongg
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