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1、ApoptosisandCellCyclePCRArray细胞凋亡与细胞周期基因芯片凋亡PCR芯片细胞凋亡PCR芯片384HT细胞周期PCR芯片ApoptosisPCRArray凋亡PCR芯片CatalogNo.PAHS-012A(人)CatalogNo.PAMM-012A(小鼠)CatalogNo.PARN-012A(大鼠)TheApoptosisRT²Profiler™PCRArrayprofilestheexpressionof84keygenesinvolvedinapoptosis,orprogra
2、mmedcelldeath.ThearrayincludestheTNFligandsandtheirreceptors;membersofthebcl-2,caspase,IAP,TRAF,CARD,deathdomain,deatheffectordomain,andCIDEfamilies;aswellasgenesinvolvedinthep53andATMpathways.Usingreal-timePCR,youcaneasilyandreliablyanalyzeexpressionofafoc
3、usedpanelofgenesrelatedtoapoptosiswiththisarray.细胞凋亡RT²Profiler™PCRArray可以同时测定84个与凋亡即细胞程序性死亡有关的关键基因。其中包括TNF配基及其受体,Bcl-2家族成员、caspase、IAP、TRAF、CARD、死亡结构域、死亡效应结构域和CIDE家族,同时还包括p53和ATM信号通路相关的基因。利用实时定量PCR,你可以方便并且可信地对与凋亡相关的基因进行同时检测。TNFLigandFamily:CD40LG(TNFSF5),F
4、ASLG(TNFSF6),LTA,TNF,TNFSF10,TNFSF7,TNFSF8.TNFReceptorFamily:CD40(TNFRSF5),FAS(TNFRSF6),LTBR,TNFRSF10A,TNFRSF10B,TNFRSF11B,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF7,TNFRSF9.Bcl-2Family:BAD,BAG1,BAG3,BAG4,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L11,BCL2L2,
5、BCLAF1,BID,BIK,BNIP1,BNIP2,BNIP3,BNIP3L,HRK,MCL1.CaspaseFamily:CASP1,CASP10,CASP14,CASP2,CASP3,CASP4,CASP5,CASP6,CASP7,CASP8,CASP9.IAPFamily:BIRC1,BIRC2,BIRC3,BIRC4,BIRC6,BIRC8.TRAFFamily:TRAF2,TRAF3,TRAF4.CARDFamily:APAF1,BCL10,BIRC2,BIRC3,CARD4,CARD6,CARD
6、8,CASP1,CASP2,CASP4,CASP5,CASP9,CRADD,NOL3,PYCARD,RIPK2.DeathDomainFamily:CRADD,DAPK1,FADD,FAS(TNFRSF6),TNFRSF10A,TNFRSF10B,TNFRSF11B,TNFRSF1A,TNFRSF21,TNFRSF25,TRADD.DeathEffectorDomainFamily:CASP8,CASP10,CFLAR,FADD.CIDEDomainFamily:CIDEA,CIDEB,DFFA.p53and
7、DNADamageResponse:ABL1,AKT1,APAF1,BAD,BAX,BCL2,BCL2L1,BID,CASP3,CASP6,CASP7,CASP9,GADD45A,TP53,TP53BP2,TP73.Anti-apoptosis:AKT1,BAG1,BAG3,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L2,BFAR,BIRC1,BIRC2,BIRC3,BIRC4,BIRC6,BIRC8,BNIP1,BNIP2,BNIP3,BRAF,CASP2,CFLAR,FAS(TNFRS
8、F6),IGF1R,MCL1,TNF,TNFRSF7.TNF配基家族;TNF受体家族;Bcl-2家族;Caspase家族;IAP家族;TRAF家族;CARD家族;死亡结构域家族;死亡效应结构域家族;CIDE结构域;P53和DNA损伤反应有关基因;抗凋亡基因ApoptosisPCRArray384HT细胞凋亡PCR芯片384HTCatalogNo.PAHS-3012A(人)TheHumanApopto