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1、【摘要】目的回顾性研究卵巢癌手术时淋巴结清扫范围、数目、转移和预后的关系。方法行全子宫双附件切除术(TAHBSO)或联合腹膜后+髂窝淋巴结扩大清扫的卵巢癌标本,全数摘取淋巴结,比较TAHBSO和扩大清扫的淋巴结数目并判断预后。结果本组51例共取淋巴结663枚,平均13枚/例。全子宫切除5枚/例,全卵巢切除9枚/例,腹膜后淋巴结切除8枚/例,髂窝7枚/例。FIGO分期Ⅰ、Ⅱ、Ⅲ、Ⅳ期3年生存率分别为36%、15%、6%、0。结论淋巴结转移是卵巢癌扩散的重要途径,不论其局部浸润程度,均须扩大淋巴结切除范围;保护生育功能的手术不影响腹膜后淋巴结切除数目。 【关键词】卵巢肿瘤
2、;淋巴转移;分期;预后 Therelationshipbetweentheresectionextentandnumberoflymphnodedissectedandtheeffectofmetastasislymphnodenumberontheprognosisofovarycancer XUPing-ping,YUYong-zhong,CHENHong-ling,etal. DepartmentofObstetricsandGynecology,The81stHospitalofPLA,Nanjing210002,China 【Abstract】Obje
3、ctiveTostudytherelationbetweenthesurgicalextentandnumberoflymphnodedissectionandtheeffectofmetastasislymphnodenumberontheprognosisofovarycancer.MethodsFifty-onepatientswithovarycancerunderwentTAHBSOorExpandclearingoperation,andallthelymphnodewereharvestedfromspecimen.Thenumberoflymphnode
4、dissectioninTAHBSOwascomparedwiththatinExpandclearingoperation.ResultsAtotalof663lymphnodeswereobtainedfromthe51specimens,themeanwas13percase.Therewere5percasewithtotalovaryandwombresection9percasewithtotalovary,8percasewithretroperitoneallymphnodesclearing,and7percasewithiliacfosslymphn
5、odes.AccordingtothenewFIGOstagesystem,the5yearssurvivalofⅠⅡⅢⅣwere36%、15%、6%and0respectively.ConclusionAlongwiththewideinvasionofthecarcinoma,wideresectionwithextendedlymphnodedissectionismandatory,reservedthebreedingfunctionoftheoperationhasnoinfluenceonthenumberofharvestedlymphnode. 【K
6、eywords】ovarycarcinoma;lymphaticmetastasis;staging;prognosis 卵巢肿瘤居妇科恶性肿瘤死因之首,本研究探讨卵巢癌淋巴结清扫的范围、数目和转移数目,并证实系统性扩大根治对预防卵巢癌术后的复发和转移有一定作用。 1资料与方法 1.1一般资料收集1989~2004年我科有病理学淋巴结检查的卵巢癌规范化手术病例51例(排除远处转移病7例),年龄21~67岁。 1.2方法卵巢癌手术局部淋巴结按盆腔、腹膜后、髂窝3处编号;手术切除范围:若肿瘤局限于卵巢包膜完整且患者要求保护生育功能,行单侧卵巢切除术;若侵及子宫,行全
7、子宫双附件切除术(TAHBSO术);若卵巢癌有外侵的做联合腹膜后腹腔动脉旁和髂窝淋巴结清扫。近3年来凡对Ⅱ~ⅢlocatedintheTomb,DongShenJiabang,deferthenextdayfocusedontheassassination.Linping,Zhejiang,1ofwhichliquorwinemasters(WuzhensaidinformationisCarpenter),whogotAfewbayonets,duetomissedfatal,whennightcame期卵巢癌施行全子宫双附件切除术的,