正常人不确定奖赏抉择加工激活脑区的分析

正常人不确定奖赏抉择加工激活脑区的分析

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时间:2018-08-08

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1、GuoZJ,etal./NeuralRegenerationResearch.2013;8(35):3344-3352.Brainareasactivatedbyuncertainreward-baseddecision-makinginhealthyvolunteers****ZongjunGuo1,2,JuanChen1,2,ShienLiu2,3,YuhuanLi4,BoSun4,ZhenboGao41SpecialHealthCareDepartment,AffiliatedHospitalo

2、fMedicalCollege,QingdaoUniversity,Qingdao266003,ShandongProvince,China2TheInstituteofBrainScience&HumanResourceManagementofQingdaoUniversity,Qingdao266003,ShandongProvince,China3DepartmentofMedicalImaging,AffiliatedHospitalofMedicalCollege,QingdaoUniver

3、sity,Qingdao266003,ShandongProvince,China4QingdaoMentalHealthCenter,Qingdao266034,ShandongProvince,ChinaCorrespondingauthor:ZongjunGuo,M.D.,Chiefphysician,Professor,SpecialHealthCareDepartment,AffiliatedHospitalofMedicalCollege,QingdaoUniversity,Qingdao

4、266003,ShandongProvince,China;theInstituteofBrainScience&HumanResourceManagementofQingdaoUniversity,Qingdao266003,ShandongProvince,China,guozjj@163.com.ShienLiu,Master,Attendingphysician,theInstituteofBrainScience&HumanResourceManagementofQingdaoUnivers

5、ity,Qingdao266003,ShandongProvince,China;DepartmentofMedicalImaging,AffiliatedHospitalofMedicalCollege,QingdaoUniversity,Qingdao266003,ShandongProvince,China,shien_28@126.com.Received:2013-07-24Accepted:2013-10-20(N20121113002)Acknowledgments:Weareveryg

6、ratefultoXuWJfromtheDepartmentofMedicalImaging,AffiliatedHospitalofMedicalCollege,QingdaoUniversity,China,forassistancewiththedesignofthemethods.ResearchHighlights(1)Comparedwithdecision-makinginthe‘certain’condition,theventrolateralprefrontallobe,front

7、alpoleoftheprefrontallobe,orbitofrontalcortex,precentralgyrus,inferiortemporalgyrus,fusiformgyrus,supramarginalgyrus,inferiorparietallobule,andcerebellarposteriorlobeexhibitedgreateractivationinthe‘risk’condition.Comparedwithdecision-makinginthe‘certain

8、’condition,thefrontalpoleoftheprefrontallobewasstronglyactivatedinthe‘ambiguous’condition.Comparedwiththe‘risk’condition,thedorsolateralprefrontallobeandcerebellarposteriorlobeshowedsignificantlygreateractivationinthe‘ambiguous’c

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