尿路感染与尿路结石的相关性研究

《尿路感染与尿路结石的相关性研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、尿路感染与尿路结石的相关性研究【摘要】目的：探讨尿路感染与尿路结石的相互关系。方法：收集120例经开放手术或腹腔镜手术取出尿路结石的住院患者。所有患者术前连续3天取晨尿行中段尿培养，术中取结石处尿液行细菌培养，取出的结石行消毒前培养和消毒后培养。结果：120例尿路结石，感染石占38例(31.6%)。感染石细菌种类以大肠埃希菌和表皮葡萄球菌为主。38例感染石由厌氧培养法检出25例(65.8%)，普通培养法检出13例(34.2%)，差异有统计学意义(P<0.05)。术中结石处尿液细菌培养阳性仅见于感染石患者，且菌种与结石菌种相同。感染石与非感染石患者的中段尿

2、、术中尿细菌培养阳性比例分别为44.7%、68.4%和4.9%、0%，临床尿路感染发生率分别为18.4%和2.4%，差异有统计学意义，P<0.01。38例感染石中37例合并上尿路梗阻，而且7例有临床尿路感染的患者均合并上尿路梗阻。结论：感染石容易导致尿路感染。伴有上尿路梗阻的结石比不伴有上尿路梗阻的结石与微生物有更密切的关系。感染石常伴有亚临床尿路感染。常见尿路致病菌的培养基和培养方法有待进一步改进，以血液增菌液作为培养基，并采用厌氧培养法更有利于细菌生长。【关键词】尿路结石;感染石;细菌培养;尿路感染　　[Abstract]Objective:Todi

3、scussthecorrelationbetweenUrinarytractinfectionandlithangiuria.Methods:One9hundredandtwentypatientswithlithangiuriawereenrolledinthestudyfromShuyangXieheHospital;theyhadbeenperformedopenoperationorlaparoscopicoperation.Midstreamurineculturewasobtainedbeforeoperationcontinuous3daysw

4、ithoutantibiotic.Intraoperativeurinecultureorcottonswabcultureofstoneincarceratedmucosalsurface，preandpoststerilizedstoneculturewerealsocarriedout.Results：Among120patientswithlithangiuria，thestonecultureshowedpositive(infectiousstone)in38cases(31.6%).Thereweremanykindsofbacteria,

5、mainlyincludingEscherichiacoilandStaphylococcusepidermidis,inthoseinfectiousstones.Inthoseinfectiousstones，25cases(65.8%)weredetectedbyanaerobicculture，others(34.2%)byordinaryculture.Therewassignificantdifferencebetweentwoculturalmethods.Onlyinpatientswithinfectiousstones，theintraop

6、erativeurinecultureorcottonswabcultureshowedpositiveandwiththesamebacteria.Theinfectionratesofmidstreamandintraoperativeurineinpatientswithinfectiousstonesweresignificantlyhigherthanthosewithnoninfectiousstones(44.7%vs4.9%and68.4%vs0%,respectively).Clinically,theincidenceofurinary

7、tractinfectionwas18.4%forpatientswithinfectiousstonesand2.4%forthosewithnoninfectiousstones.Thirtyseven9casesofinfectiousstoneswereinobstructionofupperurinarytract,7casesofurinarytractinfectionwereinobstructionofupperurinarytract.Conclusions：Infectiousstoneseasilyresultinurinarytr

8、actinfection.Thesto