lasik术中负压吸引时间对猪角膜瓣厚度和直径的影响

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1、LASIK术中负压吸引时间对猪角膜瓣厚度和直径的影响作者：马小力,徐建刚，刘汉强【摘要】　　目的：探讨准分子激光原位角膜磨镶术（LASIK）术中负压吸引时间对角膜瓣厚度和直径的影响。方法：根据负压吸引时间的不同将60只猪眼随机分为3组：组1（10s）、组2（20s）和组3（30s），使用法国产MoriaM2型角膜板层刀分别吸引角膜10s，20s和30s后切削角膜瓣，利用角膜超声测厚仪测量角膜瓣厚度，应用镀铬游标卡尺测量角膜瓣直径。结果：组1、2和3角膜瓣厚度分别为146.05±13.46，157.35±18.95和169.25±21.02μm，各组间比较有显著性差异(P＝0.001)。各组的平

2、均角膜瓣直径分别为8.63±0.19mm（组1，10s），8.89±0.24mm（组2，20s）和9.06±0.18mm（组3，30s）。各组间比较有显著性差异(P<0.01)。结论：LASIK术中随着负压吸引时间的延长，角膜瓣厚度和直径均增加。【关键词】负压吸引；角膜瓣厚度；LASIK　　Abstract　AIM:Todeterminetheeffectofsuctiondurationonthicknessanddiameterofcornealflapcreatedbymicrokeratomeinporcineeyesinlaserinsitukeratomileusis(LA

3、SIK).METHODS:Sixtyporcineeyeswererandomlyassignedto12threegroupsaccordingtodifferentsuctiondurations:group1(10seconds),group2(20seconds),andgroup3(30seconds).AMoriaM2microkeratome(Moria,France)witha160μmheadwasusedtocreateacornealflap.Cornealflapthicknesswasmeasuredbyautomatedultrasonicpachymetry,an

4、dtheflapdiameterwasmeasuredbyaverniercaliper.RESULTS:Theflapthicknessofgroup1,group2andgroup3was146.05±13.46μm,157.35±18.95μmand169.25±21.02μm,respectively.Therewasastatisticallysignificantdifferenceamongthreegroups(P=0.001).Themeanflapdiameteringroups1,2and3was8.63±0.19mm,8.89±0.24mmand9.06±0.18mm,

5、respectively.Astatisticallysignificantdifferencewasfoundamonggroups(P<0.01).CONCLUSION:InLASIKinporcineeyes,anincreaseinsuctiondurationresultedinathickerandgreaterflap.　　KEYWORDS:suctionduration;lamellarcornealflapthickness;LASIK　　INTRODUCTION　　Sinceitsintroductionin1990[1],laserinsitukeratomil

6、eusis(LASIK)hasbecomecurrentlythemostfrequently12usedsurgicaltreatmenttocorrectrefractiveerrorsworldwide[2,3].LASIKinvolvesaprimaryprocedureofcreatingacornealflapbymicrokeratome.Theflapthicknessbasedonthedistancebetweenthefixedmicrokeratomeplateandtheedgeofthemetalblade[4].Somestudiesfoundvariablest

7、hataffectLASIKflapthicknessincludecornealcurvature,cornealthickness,theamountofvacuumobtainedduringtheprocedure,microkeratomebladetranslationandoscillationrates,andbladereuse[510].Ourstudyexploredthe