17种抗菌药物对儿科常见致病菌敏感性分析.doc

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1、17种抗菌药物对儿科常见致病菌敏感性分析【摘要】目的：了解抗菌药物药敏现状，为抗菌药物临床合理使用提供资料。方法：统计湖南省郴州市第一人民医院儿童医院2007年住院患儿8种检出菌对17种抗菌药物的药敏试验结果并与其他地区结果比较。结果：G+球菌对万古霉素、亚胺培南西司他丁、氨苄西林舒巴坦、头孢噻肟、头孢唑林、头孢呋辛、头孢他啶、苯唑西林、青霉素、红霉素敏感率分别为99.3%、97.7%、89.0%、87.3%、86.9%、84.6%、80.8%、60.3%、45.2%、36.7%；G-杆菌对头孢他啶、氯霉素、亚胺培南西司他丁、头孢哌酮、氨曲南、头孢

2、噻肟、哌拉西林、头孢曲松、氨苄西林舒巴坦、头孢呋辛、头孢噻吩、氨苄西林敏感率分别为76.9%、74.5%、68.2%、58.2%、53.5%、51.5%、51.1%、36.9%、33.1%、15.2%、9.6%、7.8%；G-杆菌对头孢曲松、头孢噻肟、头孢哌酮敏感率较其他地区低，对头孢他啶敏感率高；G+球菌对青霉素、头孢唑林、头孢噻肟、苯唑西林、氨苄西林/舒巴坦敏感率高；检出菌对万古霉素、亚胺培南西司他丁敏感率相当。结论：要加强临床分离菌对抗菌药物敏感性监测。【关键词】抗菌药物；儿童；药敏实验Ananalysisonthesensitivityof1

3、7antibacterialstopathogenicbacteriacommonlyfoundinchildrenLINJie1,LIUQiaotu2,PENGHuabao1(1.TheChildrensHospitalofFirstPeoplesHospitalofChenzhou,HunanProvince,HunanChenzhou423000,China;2.TheCentralHospitalofFirstPeoplesHospitalofChenzhou,HunanProvince,HunanChenzhou423000,Chin

4、a)［Abstract］Objective:Togetinformationonthecurrentstatusofantibioticsandtoprovidedataforrationaluseofthesedrugs.Methods:Theresultsofdrugsensitivetestsininpatientsofthechildrenshospitalwerestatisticallyprocessed.Thetestscovered17antibioticsandtheresultswerecomparedwiththoseobtain

5、edbyotherhospitals.Results:ThesensitiveratesofG+coccitovancomycin,imipenemcilastatin,ampicillinsulbactam,cefotaxime,cefazolin,cefuroxime,ceftazidime,oxacillin,benzylpenicillin,erythromycinwere99.3%,97.7%,89.0%,87.3%,86.9%,84.6%,80.8%,60.3%,45.2%,36.7%amdofG-bacillitoceftazidime

6、,chloramphenicol,imipenemcilastatin,cefoperazone,aztreonam,cefotaxime,piperacillin,ceftraxone,ampicillinsulbactam,cefuroxime,cephalothin,ampicillinwere76.9%,74.5%,68.2%,58.2%,53.5%,51.5%,51.1%,36.9%,33.1%,15.2%,9.6%,7.8%,respectively.ThesensitiveratesofG-bacillitoceftriaxone,ce

7、fotaxime,cefoperazonewerelowerthanthoseinother3hospitals;thesensitiveratesofG+coccitobenzylpenicillin,cefazolin,cefotaxime,oxacillin,ampicillinsulbactamwerehigherthanotherhospitals.Conclusions:Moreattentionshouldbepayedtothedrugresistanceofthebacteriaclinicallyisolated.［Keywords

8、］Antibiotics;Children;Drugsensitivetest