microarrays for an integrative genomics computational molecular biology - isaac s. kohane, alvin kho, atul j. butte

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1、MicroarraysforanIntegrativeGenomicsTableofContentsMicroarraysforanIntegrativeGenomics........................................................................................1Foreword.............................................................................................

2、...............................................2Preface................................................................................................................................................3Acknowledgments............................................................

3、........................................................4Chapter1:Introduction.....................................................................................................................71.1TheFutureIsSoBright…........................................................

4、..........................................71.2FunctionalGenomics.........................................................................................................91.2.1Informaticsandadvancesinenablingtechnology..................................................121.2.2W

5、hydoweneednewtechniques?.........................................................................141.3MissingtheForestfortheDendrograms,orOneAspectofIntegrativeGenomics..........151.3.1Sociologyofafunctionalgenomicspipeline....................................................

6、.......181.4FunctionalGenomics,NotGenetics................................................................................191.4.1Insilicoanalysiswillneversubstituteforinvitroandinvivo...................................211.5.1BiologicalcaveatsinmRNAmeasurements...............

7、............................................231.5.2Sequence−levelgenomics......................................................................................271.5.3Proteomics...................................................................................................

8、...........291.5BasicBiology...............................................