hardy-weinberg平衡检验计算方法

hardy-weinberg平衡检验计算方法

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时间:2018-07-15

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1、12345678910111213141516171819202122232425262728293031323334353637/*  *Copyright(c)2009TheBroadInstitute  *  *Permissionisherebygranted,freeofcharge,toanyperson  *obtainingacopyofthissoftwareandassociateddocumentation  *files(the"Software"),todealintheSoftwarewithout  *re

2、striction,includingwithoutlimitationtherightstouse,  *copy,modify,merge,publish,distribute,sublicense,and/orsell  *copiesoftheSoftware,andtopermitpersonstowhomthe  *Softwareisfurnishedtodoso,subjecttothefollowing  *conditions:  *  *Theabovecopyrightnoticeandthispermissio

3、nnoticeshallbe  *includedinallcopiesorsubstantialportionsoftheSoftware.  *  *THESOFTWAREISPROVIDED"ASIS",WITHOUTWARRANTYOFANYKIND,  *EXPRESSORIMPLIED,INCLUDINGBUTNOTLIMITEDTOTHEWARRANTIES  *OFMERCHANTABILITY,FITNESSFORAPARTICULARPURPOSEAND  *NONINFRINGEMENT.INNOEVENTSHAL

4、LTHEAUTHORSORCOPYRIGHT  *HOLDERSBELIABLEFORANYCLAIM,DAMAGESOROTHERLIABILITY,  *WHETHERINANACTIONOFCONTRACT,TORTOROTHERWISE,ARISING  *FROM,OUTOFORINCONNECTIONWITHTHESOFTWAREORTHEUSEOR  *OTHERDEALINGSINTHESOFTWARE.  */  packageorg.broad.tribble.util.popgen;  /** *TheBroadI

5、nstitute *SOFTWARECOPYRIGHTNOTICEAGREEMENT *Thissoftwareanditsdocumentationarecopyright2004bythe *BroadInstitute/MassachusettsInstituteofTechnology.Allrightsarereserved. * *Thissoftwareissuppliedwithoutanywarrantyorguaranteedsupportwhatsoever.Neither *theBroadInstituteno

6、rMITcanberesponsibleforitsuse,misuse,orfunctionality. */  /** 3839404142434445464748495051525354555657585960616263646566676869707172737475*ThisclasscalculatesaHardyWeinbergp-valuegiventhreevaluesrepresenting *theobservedfrequencesofhomozygousandheterozygousgenotypesinthe

7、 *testpopulation. * *@authorBobHandsaker */ publicfinalclassHardyWeinbergCalculation{   /**   *Thisclassisnotinstantiable.   */   privateHardyWeinbergCalculation(){   }    /**   *Calculatesexacttwo-sidedhardy-weinbergp-value.Parameters   *arenumberofgenotypes,numberofrar

8、eallelesobservedand   *numberofheterozygotesobserved.   *   *(c)2003JanWigginton,GoncaloAbecasis(goncal

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