强脉冲光及脉冲染料激光595nm治疗面部毛细血管扩张比较探究

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1、强脉冲光及脉冲染料激光595nm治疗面部毛细血管扩张比较探究[摘要]目的：评价强脉冲光（IntensePulsedLight，IPL）560～1200nm/590～1200nm和脉冲染料激光595nm不同波长治疗面部毛细血管扩张症的临床有效性。方法：301例患者随机分为3组，A组(IPL560～1200nm)124例，B组(IPL590～1200nm)79例，C组(脉冲染料激光595nm)98例。分别治疗1～4次，间隔时间4～6周。观察其血管清除率。结果：A、B、C组术中血管完全消失分别为66例(53.23%

2、)、34例(43.04%)、74例(75.51%)；治愈分别为79例(63.71%)、41例(51.90%)、81例(82.65%)；平均治愈次数分别为2.66次、2.85次、1.65次。A、B、C三组总体比较差别具有统计学意义；A、B两组比较差别具有统计学意义；A、C两组和B、C两组比较差别具有统计学意义。结论：IPL560～1200nm/590～1200nm和脉冲染料激光595nm三种波长对面部毛细血管扩张均有可靠疗效，脉冲染料激光595nm波长治愈率优于IPL560～1200nm/590～1200nm波

3、长。[关键词]面部毛细血管扩张症；IPL；脉冲染料激光；疗效；临床研究[中图分类号]R751[文献标识码]A[文章编号]1008-6455（2009）02-0221-0410Comparisonofintensepulsedlightto595nmpulseddyelaserfortreatmentoffacialtelangiectasia:apilotstudyWANGYong-xian,YINGZhao-xia,LIUPing,WangQiong-yu,GEWen-yu,QIAOLi(Departmen

4、tofDermatology,theSecondHospitol,Xi’anJiaotongUniversity,Xi’an710004,Shaanxi,China)Abstract:ObjectiveTheaimofthisstudyistoevaluateefficacyofintensepulsedlight(IPL560～1200nm/590～1200nm)andpulseddyelaser(595nm)intreatmentforfacialtelangiectasia.Methods301cons

5、ecutivepatientswithfacialtelangiectasiawererandomlydividedintothreegroups:groupA(124)weretreatedwithIPL560～1200nm;groupB(79)weretreatedwithIPL590～1200nm;groupC(98)weretreatedwithpulseddyelaser(595nm).TheyweretreatedoneandtofourtimeswithIPLorPDL.Theintervalw

6、asfourtosixweeksbetweentwotreatments.Theratioofelangiectasiadisappearedwasobserved.ResultsTheproportionofelangiectasiadisappearedentirelyfromgroupA,10groupBandgroupCwere53.23%,43.04%and75.51%respectively.Thecureratewere63.71%(groupA),51.90%(groupB)and82.65%

7、(groupC)respectively.Theadvantagenumberoftreatmenttimeswere2.66(groupA),2.85(groupB)and1.65(groupC)respectively.ThereissignificantdifferencebetweengroupAandgroupC,orgroupBandgroupC.ThereisnodifferencebetweengroupAandgroupB.ConclusionThethreegroupslaserandli

8、ghtsourceswerebothefficienttotreatfacialtelangiectasia.ThisstudysuggestedthatPDListhesuperiortoIPL560～1200nm/590～1200nmintreatmentforfacialtelangiectasia.Keywords:facialtelangiectasia;IPL;，pulseddyelas