欢迎来到天天文库
浏览记录
ID:58930398
大小:3.78 MB
页数:42页
时间:2020-09-28
《细菌形态结构ppt课件.ppt》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、MedicalMicrobiology一conceptofmicrooranism:二typeofmicroorganism:1non-celltype2prokaryotes3eukaryotes三generalpropertiesofM:1tinyinsize2simpleinstructure3activeinmetabolism4fastrateinmultiplication5easyinvariation6widelydistributed四relationshiptohuman(一)C.Ncirculationinnat
2、ure(二)inindustry、agricuture、medicine(三)makeupofnormalfloraofhumanbeing1anti-pathogen2providenutrition(四)someMarepathogens1pathogens2opportunisticpathogens五history:leeuwenhoek.1676.microscopy(>200times)Pasteur(1822-1895):1yeastcellscausewinessour2pebrinecausedbyprotozoa
3、n3spontaneousgenerationcontroversy4chickens:42℃,donotacquireanthrax37℃,do5vaccineforrabieskoch:(1843—1910)1cultivationtechniques2staining3isolatedTB4Koch’spostulates:①microbesareobservedintissuespecimensfromdeadanimals;②isolatedandgrowninpureculture;③inoculatedtoa
4、healthanimal;④thediseaseisproducedintheanimal;⑤then1⑥then2六objectofmedicalmicrobiologypathogens七whywestudymedicalmicrobiology八howtostudy---:Chapter1.BacterialMorphologyandStructure§1.sizeandshapeofbacteriasize:tinyum(1um=1/1000mm)shape:coccus:diplo~,strepto~tetrad,sarci
5、na,staphylo~bacillus:spiralbacterium:vibriospirillum§2.structureofbacteriumStructureofBacteria:Essentialstructure:cellwallcellmembranecytoplasmnuclearmaterial(nucloid)SpecialStructurecapsuleflagellapilusspore一Essentialstructureofbacteria(一)cellwall:1peptidoglycan:(1)aba
6、ckbone(2)tetrapeptidesidechains(3)crossbridges2teichoicacid(G+)(1)membrane~(LTA)(2)wall~functions:a.majorsurfaceAgofG+b.RegulatingpassageofionsintoandoutofG+c.bindingBontohostcellsurface3G-(1)outermembrane.(2)LPSa.lipidAb.corepolysaccharidec.O-specificpolysaccharide表1
7、-1革兰阳性菌与阴性菌细胞壁结构比较强度较坚韧较疏松厚度20~80nm10~15nm肽聚糖层数可多达50层1~2层肽聚糖含量占细胞壁干重50%~80%占细胞壁干重5%~20%糖类含量约45%15%~20%脂类含量1%~4%11%~22%磷壁酸+-外膜-+细胞壁革兰阳性菌革兰阴性菌4FunctionsofCW.(1) toformtheexternalshapeofB.(2) toprotectBfromburstingduetohighosmolarity:G-5~6G+20~25(3) Abarriertocertainsubsta
8、ncesintoandoutofB.(4) TakepartinBmultiplication.(5) AssociatedwithBantigenicity.5BwithdeficiencyinCW(LForms):B
此文档下载收益归作者所有