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时间:2020-05-07
《2013年六盘水市健康人群乙型肝炎表面抗体水平监测-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·596·预防医学论坛2014年8月第2O卷第8期PrevMedTrib,Vo1.2O,No.8,Aug.2014·监测·2013年六盘水市健康人群乙型肝炎表面抗体水平监测田兴国,褚彪,朱仁珍,任艳,金宣华,林江丽,刘勇六盘水市疾病预防控制中心,贵州六盘水553001摘要:目的了解六盘水市健康人群乙型肝炎(乙肝)表面抗体水平,评价疫苗接种效果和人群免疫状况,为制定乙肝免疫规划提供依据。方法采用分层随机抽样和简单随机抽样的方法抽取健康人群血样。采用酶联免疫吸附(ELISA)法进行乙肝表面抗体检测。
2、结果检测2区县459份血样,抗一HBs阳性率66.O1。抗一HBs阳性率随年龄增高而降低(P3、heHealthyPopulation,LiupanshuiCity,2013TIANXing—Guo,CHUBiao,ZHURen-zhen,RENYan,JINXuan—hua,LINJiang—li,LIUYongLiupanshuiCityCenterforDiseaseControlandPrewention,Liupanshui,Guizhou,55300l,ChinaAbstract:ObjectiveTounderstandtheantibodylevelofthehepatit4、isBsurfaceantigenamongthehealthypopulationinLiupanshuicity,evaluatethevaccinationeffectandtheimmunestatus,SOastoprovidescientificbasisforworkingoutstrategiesforhepatitisBpreventionandcontro1.MethodsSerumsamplesofhealthypeoplewereselectedwithstrati—fi5、edrandomsamplingandsimplerandomsamplingmethod.Theantibodywasdetectedbyenzyme-linkedimmunosorbentassay(ELISA).ResultsAtotalof459serumsamplesweredetectedin2districts(counties)andtheaveragepositiverateoftheantibodywas66.01.ThepositiverateofHBsAbwasdropp6、ingalongwithincreasingagesinthehealthypopulation(Pd0.01).ThepositiverateofHBsAbinthehealthypopulationwithhepatitisBvaccinationwashigherthanwhosewithoutvaccination(PdO.05).ConclusionTheantibodylevelofthehepatitisBsurfaceantigenissignificantlyrisingamo7、ngthehealthypopulationinLiupanshuicity,sincethehepatitisBvaccinationisbroughtintoEPI.Keywords:Healthypopulation;HepatitisB;HBsAb;Monitoring乙型病毒性肝炎(简称乙肝)是严重危害人类健康样,2周岁以上人群采集静脉血不少于4ml,不满2周的全球性传染病。乙肝流行范围广,发病率高,危害性岁的儿童采集静脉血不少于2ml,现场分离血清,采大,是六盘水市常见的传染病。接种8、乙肝疫苗是预防用统一的编号方法,用冻存管盛装并冷藏(4~8。C)保和控制乙肝病毒(HBV)感染最有效、最经济的措施。存,并及时冷藏运送至区县疾病预防控制中心实验室六盘水市于2004年将乙肝疫苗纳入儿童免疫规划,低温保存(<一2o℃)。现场标本采集工作结束后,区对新生儿进行乙肝疫苗免费接种。为了解六盘水市健县疾病预防控制中心派专人用冷藏箱将血清标本运送康人群乙肝疫苗免疫水平,我们于2013年对钟山区和到六盘水市疾病预防控制中心进行统一检测。水城县459名健康人群乙肝表面抗体(抗一HBs)进行1.3
3、heHealthyPopulation,LiupanshuiCity,2013TIANXing—Guo,CHUBiao,ZHURen-zhen,RENYan,JINXuan—hua,LINJiang—li,LIUYongLiupanshuiCityCenterforDiseaseControlandPrewention,Liupanshui,Guizhou,55300l,ChinaAbstract:ObjectiveTounderstandtheantibodylevelofthehepatit
4、isBsurfaceantigenamongthehealthypopulationinLiupanshuicity,evaluatethevaccinationeffectandtheimmunestatus,SOastoprovidescientificbasisforworkingoutstrategiesforhepatitisBpreventionandcontro1.MethodsSerumsamplesofhealthypeoplewereselectedwithstrati—fi
5、edrandomsamplingandsimplerandomsamplingmethod.Theantibodywasdetectedbyenzyme-linkedimmunosorbentassay(ELISA).ResultsAtotalof459serumsamplesweredetectedin2districts(counties)andtheaveragepositiverateoftheantibodywas66.01.ThepositiverateofHBsAbwasdropp
6、ingalongwithincreasingagesinthehealthypopulation(Pd0.01).ThepositiverateofHBsAbinthehealthypopulationwithhepatitisBvaccinationwashigherthanwhosewithoutvaccination(PdO.05).ConclusionTheantibodylevelofthehepatitisBsurfaceantigenissignificantlyrisingamo
7、ngthehealthypopulationinLiupanshuicity,sincethehepatitisBvaccinationisbroughtintoEPI.Keywords:Healthypopulation;HepatitisB;HBsAb;Monitoring乙型病毒性肝炎(简称乙肝)是严重危害人类健康样,2周岁以上人群采集静脉血不少于4ml,不满2周的全球性传染病。乙肝流行范围广,发病率高,危害性岁的儿童采集静脉血不少于2ml,现场分离血清,采大,是六盘水市常见的传染病。接种
8、乙肝疫苗是预防用统一的编号方法,用冻存管盛装并冷藏(4~8。C)保和控制乙肝病毒(HBV)感染最有效、最经济的措施。存,并及时冷藏运送至区县疾病预防控制中心实验室六盘水市于2004年将乙肝疫苗纳入儿童免疫规划,低温保存(<一2o℃)。现场标本采集工作结束后,区对新生儿进行乙肝疫苗免费接种。为了解六盘水市健县疾病预防控制中心派专人用冷藏箱将血清标本运送康人群乙肝疫苗免疫水平,我们于2013年对钟山区和到六盘水市疾病预防控制中心进行统一检测。水城县459名健康人群乙肝表面抗体(抗一HBs)进行1.3
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