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时间:2020-05-04
《体素内不相干运动扩散加权成像对肝脏良恶性肿瘤的诊断价值探讨-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、临床放射学杂志2014年第33卷第7期·1013·腹部放射学体素内不相干运动扩散加权成像对肝脏良恶性肿瘤的诊断价值探讨鲁果果,高雪梅,程敬亮,李玉博,何杰【摘要】目的探讨体素内不相干运动(IVIM)扩散加权成像对肝脏良恶性肿瘤的诊断价值。方法对临床怀疑为肝占位患者63例进行磁共振常规平扫T。WI、T:WI、DWI(b=0、800s/mm),多b值DWI及动态增强扫描,多b值DWI选用9个b值(b=0,20,50,100,200,400,600,800,1200s/mm),其中经手术病理证实、符合临床诊断或经随访证实的肝脏肿瘤性病变52例(70个病灶),全部病变分为良性组、恶性组,
2、良性组21例(32个病灶),恶性组31例(38个病灶)。多b值DWI通过AW4.5工作站测量得到快速表观扩散系数值(Fast—ADC)、慢速表观扩散系数值(Slow—ADC),快速扩散所占比率(fractionoffastADC,),并比较这些参数在肝脏良恶性肿瘤性病变中诊断价值。本研究获得伦理委员会的批准,均与所有患者签署知情同意书。结果良性组、恶性组Fast—ADC分别为(68.64±19.00)×10一mm/s、(55.79±14.98)×10一mm/s,Slow—ADC分另0为(1.88±0.43)×10一mm/s、(0.85±0.27)×10mm/s,分别为(29.75
3、±16.42)%、(22.95±8.34)%,良性组Fast—ADC、Slow—ADC和f『日均大于恶性组,良、恶性组Slow.ADC、Fast.ADC差异有统计学意义(P均<0.05),两组间无统计学意义。结论体素内不相干运动扩散加权成像参数Slow—ADC、Fast—ADC可提高肝脏肿瘤性病变的良恶性诊断及鉴别诊断的能力。【关键词】体素内不相干运动扩散加权成像肝肿瘤EvaluationoflntravoxelIncoherentMotionDifusion-WeightedImaginginDiferentiatingBenignfromMalignantHepaticNeo
4、plasmLUGuoguo,GAOXuemei,CHENGJingliang,eta1.MRDepartment,theFirstAfiliatedHospital,ZhengzhouUniversity,Zhengzhou,HenanProvince450052,P.R.China【Abstract】0bjectiveToassessthevalueofintravoxelincoherentmotiondiffusion—weightedimagingindifferentiatingthebenignhepaticneoplasmfrommalignantone.Metho
5、dsAtotalof63patientswithclinically—suspectedspace—occup—yinglesioninliverwereenrolledinthisstudy.RoutineplainMRscanning,includingTlWI,T2WI,DWI(b=0,800s/mm),multi—bvalueDWI(b=0,20,50,100,200,400,600,800and1200s/mm)anddynamiccontrast—enhancedscanning,wereperformedinal1patients.Thediagnosisin52p
6、atients(70lesionsintota1)wasconfirmedbypathology.Thepatientsweredividedintobenigngroup(n=21,32lesions)andmalignantgroup(n=31,38lesions).Fast—ADC,slow—ADC,fractionoffastADC(FFADC)weremeasuredbyusingMADCanalysissoftwareonaAW4.5workstation,andtheirvaluesindiagnosinganddifferentiatingthebenignand
7、malignanthepatictumorsweredetermined,andtheresuhswerecomparedbetweenthetwogroups.TheprospectivestudyprotocolwasapprovedbytheInstitutionalReviewBoardandwrit—ten—informedconsentwasobtainedfromallpatientspriortotheexamination.ResultsFast—ADCvalu
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